Lonza 384-well HT Nucleofector System for High-Throughput Electroporation

The Lonza 384-well HT Nucleofector System is a compact, benchtop high-throughput electroporation platform designed to facilitate efficient nucleic acid delivery across a 384-well microplate format. This system is engineered for precise electrical pulse generation and automated plate handling, enabling consistent and reproducible transfection workflows critical for gene editing, functional genomics, and molecular diagnostics research in biotechnology.

Key Technical Features:

• System Components: Includes a high-voltage power supply and an automated 384-well Nucleofector plate handler with dual retainer carousel system, compliant with SBS plate standards.
• Electroporation Control: Delivers reproducible, high-voltage pulse sequences with finely tuned electrical parameters for optimized nucleic acid transfection across all wells.
• Automated Workflow: The plate handler facilitates uniform treatment with automated carousel positioning, enhancing throughput and reducing manual variability in large-scale bioprocessing and synthetic biology applications.
• Connectivity: Equipped with HV interface, data interface, USB, and Ethernet ports allowing seamless integration with laboratory information management systems (LIMS) and remote operation.
• Power Requirements: Operates on 100-240 VAC, 50/60 Hz input.
• Dimensions & Weight:
• Plate Handler: 40×42×15 cm; 10 kg
• Power Supply: 13.5×50×45 cm; 14 kg

Applications:

• High-throughput transfection of mammalian and hard-to-transfect cells in molecular cloning workflows.
• Delivery of plasmid DNA, siRNA, and CRISPR components for gene editing and synthetic biology research.
• Screening and optimization of electroporation conditions across diverse cell types.
• Large-scale functional genomics studies and biomedical engineering assays.
• Critical platform for bioprocessing pipelines in biopharmaceutical production and molecular diagnostics.

This system supports biotechnology professionals in executing complex experiments involving live-cell imaging and fluorescence analysis by providing high reproducibility and scalability. Lonza's HT Nucleofector System is widely adopted among researchers focused on gene delivery, cell engineering, and molecular biology workflows requiring reliable electroporation in high-density formats.

Included Accessories:

• HT Nucleofector power supply
• 384-well HT Nucleofector plate handler
• Dedicated laptop pre-loaded with control software
• Standard power and communication cables

Warranty & Support:

The system is fully functional, serviced, and offered with warranty for parts and labor. Comprehensive technical consultation, installation support (available locally), and after-sales service ensure optimal operation within research and clinical laboratory settings. Shipping is insured and carefully managed with packing compliant to ISPM15 wooden crate standards for international freight.

The Lonza 384-well HT Nucleofector System represents a robust investment for laboratories seeking advanced electroporation technology to enable high-throughput gene delivery critical in molecular diagnostics, synthetic biology, and biomanufacturing research domains.