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Molecular Devices Axon 200B

UsedMolecular DevicesAmplifiersNetherlands
Procurable

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Open-circuit noise in patch mode
<15 fA (RMS) at 0.1–1 kHz
Recording bandwidth
Up to 100 kHz
Active cooling headstage
Cools input components to well below 0°C
Capacitance compensation ranges
100 pF and 1000 pF
Pipette holders
Two included, accepting glass pipettes in most standard dimensions
Availability
Procurable
Lead time
Confirmed with your quote
All 25 specifications
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Specifications 25

Brands
Molecular Devices
New/Used
Used
Open-circuit noise in patch mode
<15 fA (RMS) at 0.1–1 kHz
Recording bandwidth
Up to 100 kHz
Active cooling headstage
Cools input components to well below 0°C
Capacitance compensation ranges
100 pF and 1000 pF
Pipette holders
Two included, accepting glass pipettes in most standard dimensions
Voltage command range
±1 V
Current command range
±200 nA
Power supply
85–264 VAC (110–340 VDC), 50–60 Hz
Peak power consumption
30 W
Fuse rating
0.5 A slow (15 x 20 mm)
Line filter
RFI filter included
Line cord
Shielded line cord provided
Dimensions (L x W x H)
483 x 305 x 89 mm
Weight
5.1 kg
Headstage dimensions (L x W x H)
107 x 18 x 19 mm
Mounting plate dimensions (L x W x H)
152 x 6 x 51 mm
Seal test modes
Current steps in current clamp mode and voltage steps in voltage clamp mode
Series resistance compensation
Active in both current clamp and voltage clamp modes
Series resistance compensation modes
Prediction and correction
Low-pass filter
4-pole Bessel filter with five settings from 1 kHz up to 100 kHz
Panel meter
Displays user-selectable parameters in real time
Availability
Procurable
Lead time
Confirmed with your quote

Product description

Ultra-low noise patch clamp amplifier with active cooling and 100 kHz bandwidth for high-fidelity electrophysiology.

Axopatch™ 200B Capacitor Feedback Patch Clamp Amplifier

The Axopatch™ 200B is a premier patch-clamp amplifier designed for ultra-low-noise single-channel and whole-cell recordings. Incorporating innovative capacitor-feedback technology and active cooling, this amplifier delivers exceptional signal fidelity, making it indispensable for precise electrophysiological studies.

Key features:

  • Ultra-low noise performance: Achieves open-circuit noise levels as low as <15 fA (RMS) at 0.1–1 kHz, facilitating high-fidelity recordings.
  • Active cooling headstage: Cools input components to well below 0°C, significantly reducing thermal noise.
  • Versatile recording modes: Supports patch and whole-cell configurations with capacitance compensation ranges of 100 pF and 1000 pF.
  • Extended bandwidth: Offers recording bandwidth up to 100 kHz, capturing rapid electrophysiological events.
  • Slim headstage design: Enhances electrode access, facilitating integration with various microscope setups.

Applications:

  • Neuroscience: Investigating ion channel behaviour and synaptic transmission.
  • Cardiac physiology: Studying cardiac ion channels and arrhythmias.
  • Biotechnology: Essential for molecular cloning workflows and widely adopted in synthetic biology research.
  • Pharmacology: Assessing drug effects on ion channel activity.

Commonly used in:

  • University laboratories
  • Biomedical research centres
  • Pharmaceutical companies
  • Biotechnology firms

First released in the late 1990s, the Axopatch™ 200B remains a gold standard in patch-clamp electrophysiology, renowned for its unparalleled noise performance and versatility. Its continued relevance underscores its critical role in advancing research across multiple scientific disciplines.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 23 October 2026