Pall Allegro 200 L Single-Use Mixer System for Biopharmaceutical Mixing Applications

The Pall Allegro 200 L Single-Use Mixer System (model LGRMXTTE200L230B) delivers robust, scalable mixing designed specifically for biopharmaceutical manufacturing, including media preparation, buffer mixing, and final drug formulation. This single-use bioprocess mixer integrates with Pall’s Allegro biocontainer films, ensuring material consistency and reducing requalification efforts—a critical feature for bioprocess validation and regulatory compliance.

Key technical features include:

• 4-Pitch Blade Impeller: Provides effective, low-shear mixing ideal for sensitive biologics and shear-sensitive proteins, supporting critical applications in molecular diagnostics and synthetic biology workflows.
• Bidirectional Flow Capability: Allows clockwise (up-flow) or counterclockwise (down-flow) operation to accommodate fluids and solids with varying densities, enhancing homogeneity.
• Bag Inflation System: Ensures a controlled mixing envelope in volumes ranging from 50 to 200 liters, enabling consistent performance across bioprocess scales and supporting gas blanketing for aerobic or anaerobic cultures.
• Flush Drain Valve: Minimizes dead volume by removing settled solids and preventing material entrapment, optimizing cleaning and validation protocols.
• Optional Baffle Kit: Reduces air entrapment during higher speed operations, beneficial for delicate formulations and processes requiring minimal shear stress.

Technical specifications:

• Operating Volume Range: 50–200 L
• Motor Power: 0.37 kW with rotation speeds between 50–200 rpm
• Materials: Mixer tote in 304 stainless steel; contact components in LDPE, PS, silicone compatible with gamma irradiation up to 50 kGy
• Electrical: 230 V AC, 50 Hz, ~5.1 A current draw
• Dimensions: Footprint 1,054 mm × 748 mm; height 1,378 mm; weight ~120 kg
• Operating Conditions: Temperature range 4–40 °C; gas supply 4–6 barg for inflation and blanketing

This system is widely adopted in biotechnology and biomanufacturing, offering reliable, validated performance for media and buffer preparation, powder reconstitution, and final formulation of biologics. The Pall Allegro mixer is essential for molecular cloning workflows, bioprocess scale-up, and biopharmaceutical production pipelines, integrating seamlessly with existing single-use technologies in biologics manufacturing facilities.