Teledyne ISCO CombiFlash EZ Prep UV-VIS Preparative Flash Chromatography System

The Teledyne ISCO CombiFlash EZ Prep UV-VIS Preparative Flash Chromatography System is a versatile instrument combining prep-scale flash chromatography and preparative HPLC modes for efficient purification workflows essential in organic synthesis, natural products isolation, and biotechnology research such as molecular diagnostics and bioprocessing.

• Flow Rate Range: 5–200 mL/min with ±5% accuracy
• Pressure Capability: High-pressure operation up to 3500 psi (240 bar); flash operation up to 200 psi (13.8 bar)
• Gradient Control: Binary gradient using any two of four solvents; programmable linear, step, and isocratic gradients with ±3% accuracy
• UV-VIS Detection: Wavelength range 200 to 800 nm in ±5 nm increments, enabling selective analyte identification and fraction triggering
• Hardware: Dual piston pumps for precise gradient delivery; system dimensions approximately 43 x 43 x 67 cm, weight 37.4 kg
• Applications: Purification of synthetic organic compounds, isolation of bioactive natural products, scale-up of lead molecules for medicinal chemistry, separation of isomers and analogs
• Included Accessories: Intake hoses with caps and solvent filters, waste hoses, collection racks (various sizes available), column bypass tube, and power cable
• Additional Features: Integrated fraction collector (standard rack), software interface for instrument control and basic data handling, RFID column detection, waste and source-level sensing, high recovery rates from milligrams to tens of grams load
• Suitability: Widely adopted in synthetic biology research, biopharmaceutical production pipelines, and biotechnology labs focused on gene editing and biomanufacturing

This system is fully tested and serviced, ensuring stable flow rates without pulsation or gradient drift, critical for reproducible molecular cloning workflows and live-cell analysis preparations. It supports user-friendly operation with remote setup and training options available. Warranty coverage and after-sales technical support provide added reliability for high-demand biotech and clinical diagnostics labs.

Optimized for laboratories requiring robust preparative chromatography solutions, this system supports scalable purification processes with reliable UV detection and programmable gradients, critical for high-purity compound isolation in biotechnology and pharmaceutical research.