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GE AxiChrom 450/300 Automated Low-Pressure Chromatography Column for Bioprocessing

UsedCytivaMedium-pressure columnsUnited States

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Brands
Cytiva
New/Used
Used
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Product description

Automated low-pressure chromatography column with scalable design and intelligent packing for bioprocess manufacturing.

The GE AxiChrom 450/300 chromatography column is a low-pressure preparative chromatography system designed for scalable bioprocessing applications, including process development and full-scale manufacturing. It supports column internal diameters ranging from 300 to 1600 mm, making it essential for biopharmaceutical production pipelines and molecular diagnostics workflows.

Key technical features include:

  • Automated column packing via *Intelligent Packing*, a function of AxiChrom Master software, enabling reproducible and verified packing methods optimized for modern chromatography resins such as Capto and MabSelect SuRe families.
  • Scalable platform ensures seamless transition from laboratory process development to GMP-compliant industrial biomanufacturing.
  • Swing-out column tube design allows easy access to bed supports and O-rings, facilitating routine maintenance and cleaning.
  • Constructed from materials suitable for sanitized operations in GMP environments, supporting stringent cleaning and sanitization protocols.
  • Integration capability with slurry tanks and chromatography systems to form a closed system, critical for maintaining product sterility in molecular cloning and synthetic biology research.

This chromatography column is widely used in biotechnology and biomedical engineering domains for protein purification, gene editing product isolation, and bioprocess development. Its advanced automation and scalable design make it a preferred choice among researchers specializing in molecular diagnostics, bioprocess optimization, and live-cell imaging downstream applications.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Can't find the exact configuration?

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Last updated 11 November 2026