Cytiva AxiChrom 300/300 Axial Compression Chromatography Column for Bioprocessing

The Cytiva AxiChrom 300/300 chromatography column is a low-pressure axial compression column designed specifically for bioprocessing applications, including process development and large-scale biopharmaceutical manufacturing. With a 300 mm inner diameter and 300 mm bed height, this column supports scalable chromatography workflows from pilot to full production, essential in molecular diagnostics, synthetic biology, and biomanufacturing pipelines.

Key features include:

• Axial compression packing technology with preprogrammed automated methods ensuring reproducible bed density and column performance, critical for consistency in gene editing and bioprocessing workflows.
• A unique swing-out tube or movable adapter design that facilitates easy access to bed supports, seals, and O-rings, optimizing maintenance and sanitization processes.
• Construction compliant with GMP requirements, using materials traceable by batch and meeting regulations such as USP Class VI, 21 CFR part 177, and EMEA guidelines, supporting regulatory standards in clinical diagnostics and biopharmaceutical production.
• Capable of effective cleaning and sanitization protocols, including treatment with 1 M NaOH, ensuring removal of microbial contaminants and endotoxins, essential for sterile bioprocess chromatography.
• Flexible configuration options for variable bed heights typically ranging from approximately 100 to 500 mm, and diverse bed support types to tailor process requirements.

The AxiChrom 300/300 column is a versatile and reliable chromatography solution widely adopted in biotechnology research, live-cell imaging sample preparation workflows, and biopharmaceutical process development, making it a critical instrument for laboratories focusing on molecular biology, bioprocessing scale-up, and production of biologics.