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Pilot-scale ÄKTA Pilot 400 synthesizes 4–60 mmol oligonucleotides for clinical-grade bioprocessing with ATEX explosion proof design.
The ÄKTA Pilot 400 by Cytiva is a pilot-scale bioprocess chromatography system designed for the efficient synthesis of oligonucleotides in the 4 to 60 mmol range, ideal for early to mid-clinical trial production. It supports production of hundreds of grams of therapeutic oligonucleotide active pharmaceutical ingredients (APIs) per lot, enabling a daily manufacturing throughput.
Key technical features include:
Widely adopted in pharmaceutical oligonucleotide manufacturing and molecular diagnostics, this system is critical for applications in gene editing research, synthetic biology, and bioprocessing pipelines requiring scalable and compliant oligonucleotide production. Its compatibility with shift operations allows capacity expansion exceeding 50 kg/year, supporting biopharmaceutical production and molecular cloning workflows.
This equipment provides researchers and process engineers with a robust, scalable solution for therapeutic oligonucleotide synthesis, emphasizing safety, operational efficiency, and regulatory compliance vital for biotechnology and clinical research applications.
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We're an independent team based in The Netherlands, working with research labs and procurement teams across Europe and worldwide.
With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.
Yes. Every verified supplier states which service partners cover the instrument, and we list that alongside the offer.
Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.
Two to six weeks, depending on refurbishment scope and whether calibration is included.
We ship to 38 countries. Crating and customs handling are quoted with the instrument.
Tell us what you need and a scientist finds it for you, usually within the hour.
Last updated 4 September 2026
The middle half of the 207 with a price runs from €268 to €871.
