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Advanced Instruments 3320 Micro Osmometer for Freezing-Point Depression Osmolality Measurement

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Measurement Method
Freezing-point depression
Sample Volume
20 µL
Measurement Range
0–2000 mOsm/kg H₂O
Typical Test Time
Approximately 60 seconds
Sample Throughput
Single-sample operation
All 13 specifications
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Specifications 13

Brands
Advanced Instruments
New/Used
Used
Measurement Method
Freezing-point depression
Sample Volume
20 µL
Measurement Range
0–2000 mOsm/kg H₂O
Typical Test Time
Approximately 60 seconds
Sample Throughput
Single-sample operation
Calibration
Automated calibration routine
Data Output
RS-232 serial port
Display
Digital interface with guided prompts
Dimensions
14 x 15 x 10 in (35.6 x 38.1 x 25.4 cm)
Weight
14 lbs (6.35 kg)
Electrical
110–120V

Product description

Precise osmolality measurement using freezing-point depression with 20 µL samples, ideal for limited volume testing.

The Advanced Instruments 3320 Micro Osmometer is a laboratory-grade micro-osmometer specialized for freezing-point depression osmolality measurement using minimal sample volumes of only *20 µL*. This capability is essential for applications in molecular diagnostics, bioprocessing, and clinical research where sample conservation is critical. The instrument operates on a single-sample basis, providing rapid and controlled osmolality results in approximately *60 seconds* per test.

Key technical features include:

  • Measurement Range: 0–2000 mOsm/kg H₂O, supporting diverse biological fluids commonly analyzed in biomedical engineering and synthetic biology workflows
  • Automated calibration routines ensure accuracy and reliability, critical in biotechnology and molecular cloning workflows
  • RS-232 serial data output facilitates integration into laboratory information management systems (LIMS) for seamless data capture and compliance documentation
  • Digital interface with guided prompts enhances user operation efficiency and minimizes training requirements
  • Compact size (14 x 15 x 10 in) and moderate weight (14 lbs) support benchtop deployment in diverse lab environments
  • Designed for low sample volume analysis, making it widely adopted in synthetic biology research and essential for molecular diagnostics, especially when sample volume is a limiting factor
  • Includes specialized 20 µL ease-eject sampler (Cat# 3M0825) for precise sample handling

The 3320 is ideally suited for researchers and lab professionals engaged in biomanufacturing, cell imaging studies, and clinical diagnostics, where small-volume osmolality testing is crucial. Its single-sample operation and micro-sample format offer advantages in live-cell imaging applications and studies involving precious or limited specimens. This unit’s design supports workflows demanding accuracy and conservation, making it a preferred choice over higher volume osmometers such as the Advanced Instruments 3250.

Proper maintenance, including probe parking technique, ensures sustained performance and longevity of this critical instrument in biotech and clinical laboratories. The 3320 Micro Osmometer delivers precise, low-volume osmolality analysis, facilitating critical decision-making in advanced biotechnology research and clinical testing environments.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 23 October 2026