Zeiss AXIO Examiner.Z1 Motorized Upright Fluorescence Microscope with Water Immersion Capability

The Zeiss AXIO Examiner.Z1 is a versatile motorized upright fluorescence microscope designed for advanced biological and material science research. Featuring integrated brightfield and multi-channel fluorescence microscopy, this system supports water immersion objectives and is customizable for complex biotechnology workflows such as gene editing and molecular diagnostics.

Key technical specifications and capabilities include:

• Microscope Base: Zeiss AXIO Examiner.Z1 upright system with Examiner Control Box
• Optics and Imaging:
• Trinocular tube with 100:0/0:100/50:50 port splits for eyepiece and camera use
• Standard eyepieces: PI 10x/23 with high numerical aperture objectives (5x/0.25 Fluar to 20x/0.4 LD Plan-NEOFLUAR), with optional high-end apochromatic objectives available
• Illumination:
• Fluorescence: Excelitas X-Cite 120Q 120W metal halide light source with built-in fluorescence light path and collimating adapter
• Brightfield: HAL100 12V 100W halogen lamp
• Fluorescence Filters: Five-position reflector turret holding multiple filter cubes; includes three new filter sets selectable from DAPI, FITC/EGFP, TRITC/Cy3, Texas Red, and Cy5, enabling multi-label fluorescence with dyes such as AlexaFluor and DyLight series
• Motorized Automation:
• Motorized XY stage (PRIOR H12PALSM/B) with joystick controller
• Motorized Z-axis focus with automatic parfocality adjustment and recall of saved focus positions
• Motorized fluorescence filter turret, epi-fluorescence shutter, and light source intensity control, facilitating automated multi-position, multi-slice (Z-stack), and time-lapse imaging
• Camera and Software:
• 8.3 MP color CMOS camera (Bestscope), compatible with BestScope Image Capture and open-source Micro-Manager software for image acquisition, annotation, calibration, and quantitative analysis
• Sample Compatibility: Slides, microplates, and petri dishes supported, suitable for live-cell imaging, fixed specimen fluorescence studies, and high-throughput scanning
• Customization and Upgrade Options: Supports addition of phase contrast, DIC, polarization modules; enhanced fluorescence light sources including LED or xenon; sCMOS and EMCCD cameras for advanced bioprocessing imaging needs; motorized high-speed shutters and stage upgrades for biomanufacturing workflows
• Applications: Widely adopted in neuroscience, developmental biology, molecular diagnostics, and synthetic biology research for fluorescence protein localization, immunolabeling, live-cell time-lapse, and automated quantitative imaging critical in biopharmaceutical production pipelines.

This microscope undergoes rigorous preventive maintenance and quality verification, including checks on optical field uniformity, fluorescence intensity at specimen plane, and precise motorized component function. It is supplied with warranty coverage and optional remote or onsite training for effective operation.

The Zeiss AXIO Examiner.Z1 is an essential tool for biotechnology laboratories requiring robust, reliable, and customizable fluorescence microscopy integrated with motorized automation for enhanced imaging throughput and reproducibility.