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Thermo Scientific Multidrop Combi Automated Liquid Dispenser for Multiwell Plates

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Plate Type
6- to 1536-well plates
Volume (Metric) Range Dispensing
0.5 to 2500µL
Dispensing Precision
Small tube dispensing cassette:2uL, ±10% (typical); 10uL, ±5% (typical); >10uL, ±5% (typical) Stand tube dispensing cassette:5uL, ±3%(typical); 20uL, ±2% (typical); 100uL, ±1% (typical); >100uL, ±1% (typical)
Dispensing Accuracy
Small tube dispensing cassette:2µL, ±10% (typical); 10µL, ±5% (typical); >10µL, ±5% (typical) Stand tube dispensing cassette:5µL, ±3%(typical); 20µL, ±2% (typical); 100µL, ±1% (typical); >100µL, ±1% (typical)
Dispensing Speed
96-well plate: 10µL in 3 sec.; 20µL in 4 sec.; 100µL in 10 sec 384-well plate: 1µL in 5 sec.; 5µL in 5 sec.; 10µL in 6 sec.; 20µL in 9 sec. 1536-well plate: 1µL in 14 sec.; 5µL in 26 sec.
All 13 specifications
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Specifications 13

Brands
Thermo Fisher Scientific
New/Used
Used
Plate Type
6- to 1536-well plates
Volume (Metric) Range Dispensing
0.5 to 2500µL
Dispensing Precision
Small tube dispensing cassette:2uL, ±10% (typical); 10uL, ±5% (typical); >10uL, ±5% (typical) Stand tube dispensing cassette:5uL, ±3%(typical); 20uL, ±2% (typical); 100uL, ±1% (typical); >100uL, ±1% (typical)
Dispensing Accuracy
Small tube dispensing cassette:2µL, ±10% (typical); 10µL, ±5% (typical); >10µL, ±5% (typical) Stand tube dispensing cassette:5µL, ±3%(typical); 20µL, ±2% (typical); 100µL, ±1% (typical); >100µL, ±1% (typical)
Dispensing Speed
96-well plate: 10µL in 3 sec.; 20µL in 4 sec.; 100µL in 10 sec 384-well plate: 1µL in 5 sec.; 5µL in 5 sec.; 10µL in 6 sec.; 20µL in 9 sec. 1536-well plate: 1µL in 14 sec.; 5µL in 26 sec.
Dispensing Increments
Small tube dispensing cassette:0.5µL increments 0.5-50µL Stand tube dispensing cassette:5µL increments 5-2500µL
Volume (Metric) Dead
<1mL volume range 0.5-50?L; <7mL volume range >50?L
Interface
Serial RS-232, USB
Dimensions
14x15x9”
Weight
20lbs
Power
100 to 240V 50/60Hz

Product description

Automated reagent dispenser with 0.5–2500 µL range, compatible with plates up to 1536 wells, for precise high-throughput assays.

The Thermo Scientific Multidrop Combi is a precision automated liquid dispenser designed for reagent delivery in multiwell plates ranging from 6 to 1536 wells. It supports plate heights up to 50 mm and enables a broad volume dispensing range from 0.5 µL to 2500 µL with high accuracy and precision.

Key features include:

  • Eight-channel dispensing with fully autoclavable cassettes (small tube and stand tube options).
  • Dispensing precision: as low as ±1% typical at volumes ≥10 µL (stand tube), with increments as fine as 0.5 µL for small tube cassettes.
  • Fast dispensing rates optimized for multiple plate formats: e.g., 10 µL dispensed to a 96-well plate in approximately 3 seconds.
  • Automatic adjustment for dispensing height ensures consistent reagent delivery across plate types.
  • Full compatibility with robotic systems for integration in high-throughput screening and assay development workflows.
  • Intuitive icon-based graphical user interface with flexible FILL software for customized protocol design and extensive plate selection.
  • RFID-enabled cassette tracking available with Smart 2 cassettes, enhancing reagent management and minimizing dead volume.
  • Connectivity via Serial RS-232 and USB interfaces for streamlined laboratory integration.

This liquid dispenser system is widely adopted in biotechnology, molecular diagnostics, and drug discovery applications requiring automated, reproducible reagent dispensing across diverse plate formats. Its precision delivery supports advanced workflows such as gene editing reagent preparation, synthetic biology screening, bioprocessing assays, and molecular cloning workflows. The model’s compatibility with high-density plates and robotic automation makes it essential in biopharmaceutical production pipelines and clinical diagnostics labs requiring reliable, scalable liquid handling solutions.

Dimensions: 14 x 15 x 9 inches Weight: 20 lbs Power: 100–240 V, 50/60 Hz

Overall, the Multidrop Combi enables rapid, accurate dispensing of reagents for a wide range of laboratory applications, with emphasis on high-throughput and biotechnology-driven assay environments.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 22 October 2026