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Thermo Scientific Ion GeneStudio S5 Semiconductor Next-Generation Sequencer with Ion Chef Automation

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Sequencing Technology
Semiconductor-based next-generation sequencing
Sequencing Format
Targeted sequencing
Supported Chip Series
Ion 5 Series chips
Compatible Chip Range
Ion 510 to Ion 540 chips
Read Output Range
Approximately 2 million to 80 million reads per run, depending on chip
All 11 specifications
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Specifications 11

Brands
Thermo Fisher Scientific
New/Used
Used
Sequencing Technology
Semiconductor-based next-generation sequencing
Sequencing Format
Targeted sequencing
Supported Chip Series
Ion 5 Series chips
Compatible Chip Range
Ion 510 to Ion 540 chips
Read Output Range
Approximately 2 million to 80 million reads per run, depending on chip
Reagent Format
Cartridge-based reagents
Sample Preparation Support
Automated library preparation, template preparation, and chip loading with Ion Chef
Weight
340 lbs total
Electrical
120V

Product description

Semiconductor-based Ion GeneStudio S5 NGS system with automated sample prep for targeted sequencing and gene panels.

The Thermo Scientific Ion GeneStudio S5 is a semiconductor-based next-generation sequencing (NGS) platform optimized for targeted sequencing applications, microbial genomics, gene panels, exome sequencing, and transcriptomics. It supports the Ion 5 Series chip range (Ion 510 to Ion 540), enabling flexible throughput from approximately 2 million to 80 million reads per run, which is critical for various biotechnological and molecular diagnostics workflows.

Key technical features include:

  • Semiconductor sequencing technology delivering high-speed, cost-effective data output essential for bioprocessing and genomic research.
  • Compatibility with cartridge-based reagents for streamlined operation and reproducible results.
  • Integration with the Ion Chef System, which automates library preparation, template preparation, and chip loading to reduce hands-on time and variability, making it well-suited for biomanufacturing and synthetic biology research pipelines.
  • The system weighs 340 lbs and operates on standard 120V electrical supply.
  • The touchscreen controllers with built-in software enhance user interface for clinical diagnostics and research applications.

This turnkey solution is widely adopted among molecular biology researchers focused on molecular cloning workflows, gene editing validation, and biotechnological innovation, providing reliable sequencing data essential for next-generation genetic analysis. The Ion GeneStudio S5’s flexibility across multiple sequencing scales makes it a critical instrument in the evolving landscape of molecular diagnostics, biomedical engineering, and live-cell genomics studies.

Included components:

  • Ion GeneStudio S5 sequencer system in original packaging
  • Ion Chef System with integrated automation capabilities
  • User manuals and 30-day warranty support

This system is ideal for laboratories requiring efficient, scalable NGS solutions to accelerate research in genomics, neuroscience, and other advanced biotechnology domains.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Yes. Every verified supplier states which service partners cover the instrument, and we list that alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 19 October 2026