Invitrogen BenchPro 2100 Automated Plasmid Purification System for Maxiprep

The Invitrogen BenchPro 2100 is a benchtop automated plasmid purification system tailored for molecular biology and biotechnology laboratories requiring standardized plasmid maxiprep workflows. Designed to efficiently process one or two bacterial cultures per batch with volumes ranging from 100 to 125 mL, it completes the plasmid DNA purification cycle in approximately 90 minutes.

Key technical features include:

• Automation of *lysis, binding, washing,* and *elution* steps within a closed system, reducing hands-on time and minimizing sample-to-sample variability.
• Typical plasmid DNA yields around 750 µg with low endotoxin levels (<10 EU/µg), essential for sensitive downstream applications such as mammalian cell transfection, sequencing, PCR, cloning, and in vitro transcription, making it critical in molecular diagnostics and synthetic biology workflows.
• Disposable fluidics cards, prefilled reagents, and single-use cell liners ensure consistent preparation quality and reduce cross-contamination risks.
• Elution volume standardized at approximately 1.0 mL with purity indicated by O.D.260/280 ratios of >1.8, confirming high-quality nucleic acid isolation.

This system benefits laboratories aiming to improve reproducibility in plasmid isolation while reducing manual labor—widely used in bioprocessing, biomanufacturing, and gene editing research environments where throughput is moderate but precision and efficiency are paramount.

Its compact design (12x21x12 inches, 22 lbs) and 120 V power requirement facilitate integration into standard lab benches without major infrastructure changes. The BenchPro 2100 is an essential tool for molecular cloning workflows and is popular among researchers focused on biotechnological applications in molecular biology and clinical diagnostics.