Bio-Rad DCode System Vertical Gradient Gel Electrophoresis Mutation Detection Unit

The Bio-Rad DCode System is a precision-engineered mutation detection system designed for advanced molecular diagnostics and genetic research. It features a vertical electrode configuration and supports adapters for diverse electrophoretic techniques including SSCP (Single-Strand Conformation Polymorphism), DGGE (Denaturing Gradient Gel Electrophoresis), CDGE (Constant Denaturing Gradient Electrophoresis), and TTGE (Temporal Temperature Gradient Electrophoresis), making it widely applicable in biotechnology workflows such as gene editing validation and molecular cloning mutation screening.

Key technical specifications include:

• Sample capacity: Up to 64 samples per run, facilitating high-throughput genetic analysis.
• Run time: Minimum electrophoresis duration of 2 hours for optimal resolution of DNA variants.
• Temperature control range: Precise temperature regulation between 5°C and 70°C with a minimal ramp rate of 0.1°C/hour, essential for stable denaturing gradients.
• Gradient configuration: Supports gradients aligned parallel or perpendicular to electrophoresis flow, enhancing versatility in mutation detection protocols.
• Gel plate dimensions: Compatible with plates sized 20x16 cm, 16x16 cm, 10x16 cm, and 7.5x16 cm, enabling simultaneous processing of up to four gels per plate size.
• Exclusions: Does not include a gradient generator; must be paired with external gradient control for DGGE applications.

This system is professionally refurbished, offering reliable performance with cost-effective value, suitable for research and clinical laboratories focused on genomic variant analysis, molecular diagnostics, and synthetic biology studies. Its controlled temperature gradients and diverse adapter compatibility make it a preferred solution for biotechnology professionals aiming to enhance mutation scanning accuracy in bioprocessing and molecular cloning pipelines.