Bio-Rad DCode System Vertical Electrophoresis Mutation Detection System

The Bio-Rad DCode System is a specialized vertical gel electrophoresis instrument designed for high-sensitivity mutation detection through various thermal gradient electrophoresis techniques. It supports adapters for SSCP (Single-Strand Conformation Polymorphism), DGGE (Denaturing Gradient Gel Electrophoresis), CDGE (Constant Denaturing Gel Electrophoresis), and TTGE (Temporal Temperature Gradient Electrophoresis), making it versatile for molecular diagnostic workflows.

• Sample Capacity: Accommodates up to 64 samples per run, supporting high-throughput mutation screening essential in gene editing and synthetic biology research.
• Temperature Control: Precise thermal regulation from 5°C to 70°C with minimum temperature ramp rates as low as 0.1°C/hour, critical for resolving subtle genetic variations in bioprocessing and molecular cloning applications.
• Gradient Orientation: Allows gradients to be applied parallel or perpendicular to electrophoresis flow, optimizing separation efficiency for complex nucleic acid samples.
• Gel Plate Dimensions: Compatible with multiple plate sizes—20x16 cm, 16x16 cm, 10x16 cm, and 7.5x16 cm—enabling simultaneous runs of up to four gels depending on plate choice.
• System Configuration: Vertical electrophoresis format suited for precise mutation detection workflows relevant to biotechnology and clinical diagnostics.
• Note: Gradient generator is not included.

This refurbished DCode System offers a reliable, cost-effective solution widely adopted in molecular genetics, biopharmaceutical production pipelines, and clinical research for mutation detection tasks. Its robust design supports reproducible results in molecular diagnostics, gene editing validation, and synthetic biology experiments, making it a valuable instrument for laboratories focused on biomanufacturing and biomedical engineering.