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Thermo Scientific TSX40086A & TSX50086D Ultra-Low Temperature Freezers with V-Drive Adaptive Control

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Temperature Range
-50°C to -86°C
Refrigerant
R290 (1st stage), R170 + R290 mix (2nd stage)
Defrost
Manual
Interior Dimensions
28x26x51″ (TSX50086D) 27x22x59″ (TSX40086A)
Volume
24.1 cu. ft./682 L (TSX50086D) 19.4 cu. ft./549 L (TSX40086A)
All 14 specifications
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Specifications 14

Brands
Thermo Fisher Scientific
New/Used
Used
Temperature Range
-50°C to -86°C
Refrigerant
R290 (1st stage), R170 + R290 mix (2nd stage)
Defrost
Manual
Interior Dimensions
28x26x51″ (TSX50086D) 27x22x59″ (TSX40086A)
Volume
24.1 cu. ft./682 L (TSX50086D) 19.4 cu. ft./549 L (TSX40086A)
Box Capacity
500 2-inch boxes (TSX50086D) 400 2-inch boxes (TSX40086A)
Vial Capacity
50,000 x 2 mL (TSX50086D) 40,000 x 2mL (TSX40086A)
Shelf Weight Load Max
205 lb. / 93 kg
Power Consumption (at -70°C)
6.5 kWh/day
External Dimensions
38x38x78″ (TSX50086D) 37x33x79″ (TSX40086A)
Weight
721 lbs (TSX50086D) 573 lbs (TSX40086A)
Power
208/230 V, 60 Hz, 5.1A (TSX50086D) 115V, 60Hz, 9A (TSX40086A)

Product description

The Thermo Scientific TSX40086A and TSX50086D are advanced ultra-low temperature freezers designed for precise and energy-efficient storage of biological samples, essential in biotechnology, molecular diagnostics, and bioprocessing workflows. Featuring V-drive adaptive control technology, these ULT freezers dynamically adjust compressor output according to real-time conditions such as door openings and ambient temperature changes, ensuring consistent -80°C storage and rapid recovery, which is critical for maintaining sample integrity in gene editing, synthetic biology, and biomanufacturing environments.

Key technical features include:

  • Temperature Range: -50°C to -86°C, ideal for cryogenic sample preservation and molecular cloning applications
  • Refrigerants: Environmentally-friendly R290 (primary stage) and R170 + R290 mix (secondary stage) for efficient cooling performance
  • Capacity & Dimensions:
  • TSX50086D: 24.1 cu. ft. (682 L) volume, supports up to 500 two-inch boxes or 50,000 x 2mL vials, external dimensions 38x38x78”
  • TSX40086A: 19.4 cu. ft. (549 L) volume, supports up to 400 two-inch boxes or 40,000 x 2mL vials, external dimensions 37x33x79”
  • Power Consumption: Approximately 6.5 kWh/day at -70°C setpoint for energy-conscious laboratory operations
  • Loading Capacity: Shelves support loads up to 205 lbs (93 kg), suitable for dense sample storage racks
  • User Interface & Data Management: Integrated onboard data center allows easy access to operational records and setup without external hardware. Compatible with Smart-Vue for remote monitoring, supporting central lab oversight and audit trails critical in clinical and research environments.
  • Ergonomic Design: Features easy-open handles and shelf-level loading to reduce strain during frequent access — vital for busy shared laboratory spaces

Extensively validated for operational stability with third-party temperature logging, the TSX series freezers guarantee reliable performance in critical biotechnology and biomedical research applications, including live-cell imaging sample storage, clinical diagnostics, and biopharmaceutical production pipelines. They are widely adopted in research facilities requiring ultra-low temperature preservation combined with energy efficiency and intelligent control systems.

This combination of capacity, adaptive compressor control, and integrated monitoring renders the Thermo Scientific TSX40086A and TSX50086D ultra-low freezers ideal for laboratories focused on long-term preservation of biological materials with stringent stability and traceability demands.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Yes. Every verified supplier states which service partners cover the instrument, and we list that alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 19 October 2026