Thermo Gibco CTS Rotea Counterflow Centrifugation System Unit 3 for Cell Processing

The Thermo Gibco CTS Rotea Counterflow Centrifugation System Unit 3 is a specialized bioprocessing instrument designed for gentle, high-efficiency cell washing, concentration, and separation. This closed sterile system employs counterflow centrifugation technology to minimize shear stress, ensuring high cell viability and recovery, which is essential for advanced cell therapy research and clinical manufacturing workflows.

Key technical specifications include:

• Maximum centrifugal force: 3000 x g
• Peristaltic pump flow rate:
• Standard kit: 5–110 mL/min
• Hi-Flow kit: 30–160 mL/min
• Centrifuge chamber volume: 10 mL
• Cell load per chamber: 5 × 10^7 to 5 × 10^9 cells
• Output cell concentration: 5 × 10^6 to 300 × 10^6 cells/mL
• Input sample volume range: 50 mL to 20 L
• Minimum output volume: 5 mL
• Maximum fluid density: 1.10 g/mL
• Weight: 44 lb (20 kg)

The system supports scalable cell processing workflows from small research samples up to clinical manufacturing volumes, making it widely adopted in molecular diagnostics, cell therapy biomanufacturing, and synthetic biology research. Its compact footprint and automated operation reduce manual labor and improve reproducibility in live-cell imaging and biotechnology experiments.

Additionally, the instrument features:

• Flexible flow control for gentle processing.
• Closed-system design to maintain sterility, critical in bioprocessing and molecular cloning workflows.
• Compatible with Thermo Fisher's CTS™ Rotea™ single-use kits for contamination-free operation.
• Tested and serviced with full functionality verification including pinch valves, peristaltic pump, camera, door lock, LEDs, and communication software interface.

This unit is commonly used for:

• Cell washing and buffer exchange in cell therapy manufacturing pipelines.
• Cell enrichment and concentration for clinical and research applications.
• Maintaining cell viability for downstream applications such as flow cytometry, gene editing, and biopharmaceutical production.

The CTS Rotea system is supported by comprehensive warranties and technical consultation, making it a reliable solution for biotechnology laboratories requiring sterile, reproducible cell separation under controlled shear conditions.