Thermo Fisher CTS Rotea Counterflow Centrifugation System for Cell Processing

The Thermo Fisher CTS Rotea Counterflow Centrifugation System Unit 2 is a specialized closed-system centrifuge designed to support sterile, scalable cell processing workflows in biotechnology and clinical cell therapy research. Utilizing counterflow centrifugation, this system enables gentle cell washing, concentration, and separation with minimized shear stress, ensuring high cell viability recovery essential in molecular diagnostics and bioprocessing applications.

Key technical specifications include:

• Centrifugal force: up to 3000 x g for efficient separation
• Centrifuge chamber volume: 10 mL capacity per run
• Peristaltic pump flow rate: 5–110 mL/min (standard kit), 30–160 mL/min (Hi-Flow kit)
• Cell processing range: accommodates input volumes from 50 mL to 20 L, supporting flexible sample sizes
• Cell count per load: processes 5 x 10^7 to 5 x 10^9 cells with output concentrations ranging from 5 x 10^6 to 3 x 10^8 cells/mL
• Maximum fluid density tolerance: 1.10 g/mL, compatible with standard cell suspensions
• Compact unit weight: approximately 20 kg (44 lb), facilitating efficient lab space utilization

This system is widely adopted in cell therapy manufacturing pipelines, gene editing workflows, and biomanufacturing processes requiring sterile, reproducible cell washing and concentration. Its closed, automated design minimizes manual intervention and contamination risk, making it critical in synthetic biology research and clinical diagnostics.

Additional features include digital control interfaces, integrated camera monitoring, pinch valve operation for flow control, and secure door locking mechanisms, supporting robust process validation and compliance in regulated environments. The system is compatible with Thermo Fisher’s proprietary single-use kits to meet GMP bioprocessing standards.

This unit has been fully tested by professional service teams confirming operational status of software communication, hardware components, and fluidics systems. It is supplied with a standard power cord and is covered by warranty options suitable for both research institutions and biopharma production sites.

Overall, the CTS Rotea system is an essential instrument for researchers and manufacturing laboratories focused on advanced cell separation, buffer exchange, and cell enrichment tasks, combining efficiency and gentle processing for high-quality downstream biological applications.