Thermo Scientific Exactive Plus EMR Orbitrap High-Resolution Benchtop Mass Spectrometer

The Thermo Scientific Exactive Plus EMR Orbitrap Mass Spectrometer is a benchtop, high-resolution mass spectrometer optimized for comprehensive biomolecular analyses including protein characterization and biopharmaceutical research. Equipped with an Orbitrap mass analyzer paired with a C-Trap, this instrument delivers exceptional resolving power of up to 140,000 FWHM and sub-ppm mass accuracy, essential for precise molecular diagnostics and synthetic biology workflows.

Key technical specifications include:

• Mass range: m/z 50–6,000 standard; extended EMR range up to m/z 20,000 for large biomolecules and native mass spectrometry applications
• Ion source: Thermo Scientific Ion Max API with H-ESI II dual desolvation probe, enabling robust electrospray ionization for proteins and monoclonal antibodies
• Scan speed: Up to 12 Hz, supporting rapid full-scan acquisition for efficient bioprocessing and metabolite identification workflows
• Ion optics: S-Lens RF ion guide enhances ion transmission for improved sensitivity in complex mixture screening
• Vacuum system: Seven-region differential vacuum maintained below 1 × 10⁻⁹ mbar using dual turbo and rotary vane pumps ensures stable instrument performance during long analytical runs
• Signal processing: 16-bit digitization provides high-fidelity data essential for molecular cloning and gene editing research platforms
• Polarity switching: Supports both positive and negative ion modes, expanding applicability across diverse analytical targets in cell imaging and biomedical engineering

This model is widely adopted in structural proteomics, native mass spectrometry, and complex biopharmaceutical pipelines, making it an indispensable tool in biotechnology laboratories focusing on synthetic biology and molecular diagnostics. Its rugged benchtop design supports integration with chromatography systems for LC-MS workflows critical in biomanufacturing quality control.

The instrument is sold as-is with no warranty or returns and has not been tested by the vendor beyond cosmetic inspection. Shipping is via freight with professional packing to ensure safe transport. Suitable consumables required include LC-MS grade reagents, nitrogen gas supply, calibration standards, and spray needles.

Ideal for university research labs, clinical diagnostic facilities, and industrial bioprocessing organizations seeking a robust, high-resolution mass spectrometer for advanced proteomic and metabolite analysis applications.