Revvity Nexcelom Cellaca PLX High Throughput Cell Counter Cytometer with Multi-Channel Fluorescence and Brightfield Imaging

The Revvity Nexcelom Cellaca PLX High Throughput Cell Counter Cytometer is a compact benchtop automated cell analyzer designed for rapid and accurate cell counting with both fluorescence and brightfield imaging modes. Ideal for biotechnology and biomedical research environments, this instrument supports high-throughput workflows essential in molecular diagnostics, bioprocessing, and cell therapy quality control.

Key technical specifications include:

• Fluorescence channels: Brightfield plus Blue, Green, Orange, Red, and Far Red for multiplexed fluorescence detection.
• Excitation LEDs: 370, 475, 531, and 628 nm wavelengths optimize excitation for common fluorophores used in cell viability and marker staining assays.
• Emission filters: Precisely matched at 452, 534, 605, 655, and 692 nm for high-contrast fluorescence discrimination.
• Sample volume range: 15 µL in slides; 50-200 µL in multiwell plates enabling adaptable throughput from single samples to large screening batches.
• Cell size detection: 5 to 80 µm diameter accommodates diverse cell types across mammalian cell cultures and biomanufacturing lines.
• Cell concentration range: Accurate quantitation between 1x10^5 to 1x10^7 cells/mL supports cell culture monitoring in biotechnology workflows.
• Automation ready: Seamless integration with robotic platforms and automated liquid handling systems facilitates scalable synthetic biology and gene editing workflows.
• Dimensions and weight: Compact footprint (33 cm W x 33 cm H x 40.6 cm D), weighing 20 kg, suitable for busy laboratory benchtops.

Included with the system are a computer equipped with Matrix software and all necessary communication and power cables. The instrument utilizes disposable counting chambers to minimize contamination risks and streamline sample processing.

Applications prominently include:

• Rapid cell viability and concentration assays vital in cell culture quality control during biopharmaceutical production pipelines.
• Preparation of samples for advanced downstream analysis techniques such as flow cytometry and genomic sequencing.
• Monitoring cell health during bioprocessing and live-cell imaging applications.
• Quality assurance in regenerative medicine and cell therapy manufacturing.

This instrument has been thoroughly tested for fluorescence intensity stability, imaging accuracy using CMOS cameras, motorized stage responsiveness and precision, and electronic noise suppression to guarantee artifact-free, reproducible data. It is backed by warranty and post-sale technical support, with remote setup training included.

The Cellaca PLX represents a critical tool for researchers in molecular biology, clinical diagnostics, and biotechnology seeking a robust, high-throughput fluorescence cell counting solution optimized for contemporary biomanufacturing and synthetic biology research environments.