Miltenyi Biotec autoMACS Pro Automated Magnetic Cell Separator

The Miltenyi Biotec autoMACS Pro Separator is a state-of-the-art automated magnetic-activated cell sorting (MACS) system designed for rapid, high-throughput separation of cells from complex samples such as whole blood and bone marrow. Utilizing 50nm superparamagnetic MACS MicroBeads conjugated to specific antibodies, this instrument enables precise isolation of target cell populations without saturating cell surface epitopes, which is critical for downstream applications including flow cytometry, FISH, and PCR.

Key technical features include:

• Twelve pre-programmed separation protocols tailored to cell frequency, antigen expression, and separation strategy, ensuring reproducibility.
• Barcode scanning for reagents automatically selects the appropriate protocol and wash cycles, enabling hands-free operation and enhanced biosafety.
• Processes up to six samples simultaneously in 5ml, 15ml, or 50ml tubes.
• Maintains samples at 4°C throughout processing with chill racks to preserve cell viability and prevent gene expression changes—essential for molecular biology and biotechnology workflows.
• Automated start-up, cleaning, shutdown, and maintenance with optimized wash and decontamination protocols reducing manual intervention.
• Compact footprint (23″ x 14″ x 16″) and 58 lbs weight facilitate benchtop use in clinical diagnostics and bioprocessing laboratories.

The autoMACS Pro is widely adopted in hematology, molecular diagnostics, bioprocessing, and cell-based research, including myeloma studies and bone marrow transplantation chimerism analysis. Its ability to isolate viable leukocyte subsets from small blood volumes without the need for gradient centrifugation makes it critical in biopharmaceutical production pipelines and synthetic biology research. This system supports high-throughput workflows in cell culture, flow cytometry, and molecular cloning applications.

Included with the system are buffer, waste, rinse, and storage bottles; a touchscreen controller with user-friendly software; columns; chill racks; and comprehensive validation documentation. The autoMACS Pro Separator exemplifies precision magnetic cell sorting for advanced biotechnological and clinical research environments.