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Thermo Scientific Q Exactive

UsedThermo ScientificMass spectrometersNetherlands
Procurable

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Mass Range
50 to 6000 m/z
Maximum Resolving Power
140,000 at m/z 200
Maximum Scan Rate
12 Hz at resolution setting of 17,500 at m/z 200
Mass Accuracy (Internal Calibration)
< 1 ppm RMS
Mass Accuracy (External Calibration)
< 3 ppm RMS
Availability
Procurable
Lead time
Confirmed with your quote
All 26 specifications
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Specifications 26

Brands
Thermo Scientific
New/Used
Used
Mass Range
50 to 6000 m/z
Maximum Resolving Power
140,000 at m/z 200
Maximum Scan Rate
12 Hz at resolution setting of 17,500 at m/z 200
Mass Accuracy (Internal Calibration)
< 1 ppm RMS
Mass Accuracy (External Calibration)
< 3 ppm RMS
Sensitivity (Full MS)
500 fg Buspirone on column S/N 100:1
Sensitivity (SIM)
50 fg Buspirone on column S/N 100:1
Dynamic Range
> 5000:1
Polarity Switching
One full cycle in < 1 sec (one full scan positive mode and one full scan negative mode at resolution setting of 17,500)
Multiplexing
Up to 10 precursors/scan
Scan Functions
SIM & PRM
Dissociation Methods
In-source CID, HCD
Ionization Mode
± ESI
Operating Modes
Full scan MS, MS/MS
Ionization Modes
ESI Pos & Neg, APCI Pos & Neg, APPI Pos & Neg
Sample Inlet
HPLC with autosampler
Ion Source
IonMax with H-ESI II probe
Sample Types
Organic and Bio-organic compounds/Polar and Non-polar compounds, Proteomic and Metabolomic samples
Dimensions
950 x 830 x 910 mm (H x D x W)
Weight
182 kg
Power Supply
2 x 230 VAC ± 10% single phase, 15 A, 50/60 Hz
Software
Xcaliber 2.1, Proteome Discoverer 1.3, Mass Frontier 7.0, MetWorks 1.3sp1, Seive 2.0, Protein Deconvolution 3.0
Availability
Procurable
Lead time
Confirmed with your quote

Product description

High-resolution accurate-mass Orbitrap mass spectrometer with quadrupole precursor selection for quantitative and qualitative analysis.

Thermo Scientific Q Exactive is a high-performance benchtop quadrupole-Orbitrap mass spectrometer designed to deliver high-confidence quantitative and qualitative analyses across diverse scientific applications.

Key features include:

  • High-resolution accurate-mass (HR/AM) Orbitrap detection: Ensures precise mass measurements for reliable compound identification.
  • Quadrupole precursor selection: Facilitates targeted analysis by isolating specific ions.
  • HR/AM Quanfirmation capability: Enables simultaneous identification, quantification, and confirmation of trace-level metabolites, contaminants, peptides, and proteins in complex mixtures within a single analytical run.
  • Fast scanning and spectral multiplexing: Compatible with ultra-high-performance liquid chromatography (UHPLC) and rapid chromatography techniques, enhancing productivity.
  • Versatile quantitation approaches: Supports selected ion monitoring (SIM), parallel reaction monitoring (PRM), and data-independent acquisition (DIA) for comprehensive analysis.

This instrument is widely applied in:

  • Proteomics: Facilitates bottom-up protein identification, semi-quantitative isotopic labeling analyses, and targeted quantification experiments.
  • Metabolomics: Identifies and quantifies metabolites in complex biological samples.
  • Pharmaceutical research: Assists in drug discovery, pharmacokinetics, and quality control processes.
  • Environmental analysis: Detects contaminants and pollutants in various matrices.
  • Food safety: Screens for residues and contaminants to ensure compliance with safety standards.

Commonly utilized in university laboratories, biomedical research centres, pharmaceutical companies, and clinical research facilities, the Q Exactive has been instrumental in advancing research since its introduction in 2011.

Its robust design and advanced capabilities make it a valuable asset for scientists seeking reliable and efficient mass spectrometry solutions.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 22 October 2026