Phenomenex SphereClone SAX Ion Exchange LC Column 25 cm × 4.6 mm, 10 µm Particle Size

The Phenomenex SphereClone SAX (00G-4160-E0) is a high-performance ion exchange liquid chromatography column designed for biomolecular separation tasks essential in molecular diagnostics and bioprocessing workflows. Featuring dimensions of *25 cm length by 4.6 mm internal diameter* and a *10 µm particle size*, this column mimics the chromatographic behavior of Waters Spherisorb columns, ensuring reliable reproducibility and separation efficiency.

Key technical specifications and features include:

• Strong Anion Exchange (SAX) stationary phase optimized for separating negatively charged biomolecules such as nucleotides, proteins, and peptides.
• Particle size of 10 µm balances resolution and flow rate compatibility with standard analytical HPLC systems.
• Column dimensions of 25 cm × 4.6 mm enable high sample capacity suited for analytical and preparative separations.
• Compatible with a wide range of aqueous and buffered mobile phases commonly employed in biotechnology and synthetic biology research.

This ion exchange LC column is widely adopted in biotechnology applications such as gene editing product purification, biopharmaceutical production pipelines, and molecular cloning workflows due to its reliable selectivity and reproducibility. The Phenomenex SphereClone SAX column supports advanced separation techniques critical for synthetic biology, molecular diagnostics, and biomanufacturing quality control.