Waters ACQUITY UPLC System with PDA Detector and SQ Single Quadrupole Mass Spectrometer

The Waters ACQUITY UPLC PDA SQ system combines ultra-performance liquid chromatography with integrated photodiode array (PDA) UV/Vis spectral detection and a single quadrupole (SQ) mass spectrometer, delivering high sensitivity and reproducibility in biochemical separations and molecular diagnostics. This modular system includes:

• PDA Detector: Photodiode array for detailed UV/Vis spectral analysis critical in analytical chemistry and quality control.
• Sample Manager: Automated sample handling with precision injection and temperature control, ideal for complex bioprocessing workflows.
• Binary Solvent Manager: Enables accurate gradient solvent delivery, essential for reproducible chromatography separations.
• SQ Mass Detector: Single quadrupole mass spectrometer providing robust mass detection for molecular identification and quantification.
• HTCH Column Heater: Ensures stable column temperature for enhanced chromatographic performance.

Designed for applications in pharmaceutical development, biotechnology research, molecular diagnostics, and environmental analysis, this system supports workflows requiring precise liquid chromatography coupled with mass spectrometric detection. Key features include error-free operation of the solvent manager and mass detector, with the PDA detector functioning but requiring lamp replacement — an important consideration for uninterrupted UV/Vis detection.

Operating at 120V/220V and 50Hz/60Hz, the unit weighs approximately 200 lb (108.86 kg), with a modular architecture providing flexibility for biomanufacturing process development and synthetic biology research. This chromatography and mass detection system is widely adopted in molecular biology laboratories and clinical diagnostics, serving critical roles in applications such as gene editing validation and bioprocess monitoring.

Its high-performance integration of UPLC and mass spectrometry makes it essential for molecular cloning workflows and biopharmaceutical production pipelines where analytical precision and sensitivity are mandatory.

This equipment is in good cosmetic condition, though full operational testing requires compatible software and computing resources, which are not included. The system’s comprehensive functionality and modular components make it a reliable solution for advanced biotechnological and chemical analytical laboratories.