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Waters Acquity M-Class Ultra Performance Liquid Chromatography System with LBSM, LSM-FL, ASM & TVM Modules

UsedWatersHPLC pumpsUnited Kingdom

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Waters
New/Used
Used
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Product description

Acquity M-Class UPLC system with multiple solvent and sample managers, critical for advanced molecular diagnostics and bioprocessing.

The Waters Acquity M-Class Ultra Performance Liquid Chromatography (UPLC) System integrates high-precision modules designed to support advanced analytical workflows in biotechnology, pharmaceutical development, and molecular diagnostics. This configuration includes:

  • Micro Binary Solvent Manager (LBSM, 186016003): delivers precise binary solvent mixing for gradient elution, essential in bioprocessing and synthetic biology research.
  • Micro Sample Manager – Fixed Loop (LSM-FL, 186016012): optimized for controlled sample injection accuracy, widely used in molecular cloning workflows and gene editing analytics.
  • Auxiliary Solvent Manager (ASM, 186016022): supports additional solvent lines for complex solvent gradients, enhancing method flexibility in biopharmaceutical production pipelines.
  • Trap Valve Manager (TVM, 186016016): manages valve switching for trap columns, improving sample cleanup and concentration in fluorescence analysis and live-cell imaging sample prep.

Mounted on the Acquity UPLC M-Class Cart, the system is engineered for seamless integration with mass spectrometry detectors, making it highly suitable for proteomics, metabolomics, and synthetic biology research applications. The system was manufactured between 2022 and 2023 and maintained under a Waters service contract, ensuring optimal performance and reliability.

Additional accessories include original spare tubing, cables, adapters, and fittings, facilitating effective system maintenance in high-throughput workflows. This modular UPLC system is extensively adopted in clinical diagnostics and biotechnology laboratories requiring robust, reproducible chromatographic separation for molecular biology and biomanufacturing projects.

*Note:* The system does not include a standalone PC or software but provides installation disks for system drivers and documentation, allowing integration into existing analytical infrastructures.

This configuration is critical for laboratories focusing on high-resolution chromatography techniques widely used in neuroscience, biomedical engineering, and synthetic biology research, enhancing analytical throughput and precision in complex biomolecular separations.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Can't find the exact configuration?

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Last updated 22 October 2026