Waters LCT Premier

LCT Premier is a benchtop time-of-flight (TOF) mass spectrometer designed to deliver high-resolution, exact mass measurements with exceptional sensitivity. This instrument is particularly valuable in the biotechnology sector, where precise molecular analysis is crucial for applications such as bioprocessing, gene editing, and synthetic biology.

Key features include:

• High-resolution oa-ToF technology: Achieves resolutions up to 10,000 FWHM, enabling accurate mass assignments.
• LockSpray dual-electrospray source: Facilitates automated exact mass measurements with sub-3 ppm RMS accuracy, enhancing confidence in analyte identification.
• ZSpray source with electrospray ionisation (ESI): Provides robust and sensitive ionisation for a wide range of compounds.
• Dynamic Range Enhancement: Offers over four orders of magnitude, ensuring both exact mass measurement and quantitative analysis across diverse sample types.

This mass spectrometer is widely utilised in:

• Proteomics: For identifying and characterising proteins and peptides.
• Metabolomics: To analyse small molecule metabolites in biological systems.
• Pharmaceutical research: For drug discovery and development processes.
• Biopharmaceutical production: Ensuring quality control and characterisation of biologics.

Commonly found in:

• University laboratories: Supporting advanced research and education.
• Biotechnology companies: Facilitating product development and quality assurance.
• Clinical research facilities: Aiding in diagnostic and therapeutic studies.

Introduced in 2004, the LCT Premier remains a relevant tool in laboratories, especially when refurbished to meet original specifications.

By integrating the LCT Premier into your laboratory, you gain a reliable solution for exact mass measurements, enhancing the accuracy and efficiency of your analytical workflows in the biotechnology industry.