Thermo Scientific LTQ Orbitrap Velos Pro Mass Spectrometer with ETD and High Resolution

The Thermo Scientific LTQ Orbitrap Velos Pro is a high-resolution mass spectrometry analyzer designed for precise molecular weight determination and advanced proteomics research. It integrates an Orbitrap mass analyzer capable of achieving resolutions greater than 100,000 at m/z 400, supporting detailed analysis of complex biological samples essential for biotechnology and molecular diagnostics applications.

Key technical features include:

• Mass range of m/z 50–4000, covering a broad spectrum suitable for intact protein and peptide characterization.
• Electron Transfer Dissociation (ETD) for sensitive post-translational modification (PTM) analysis, critical in synthetic biology and gene editing workflows.
• An efficient Higher-energy Collisional Dissociation (HCD) cell enhancing quantitation accuracy of isobarically labeled peptides, widely used in Tandem Mass Tag (TMT) experiments for multiplexed protein quantification.
• Exceptional mass accuracy with external calibration at <3 ppm and internal calibration at <1 ppm to reduce false positives in biopharmaceutical research.
• Ionization via Electrospray Ionization (ESI), standard in proteomics and metabolomics for gentle ion generation preserving molecular integrity.
• Dynamic range exceeding 5,000 within a single scan, suitable for quantitative studies in bioprocessing and molecular cloning workflows.

This instrument is valued in research fields such as cell imaging, protein chemistry, and neuroproteomics, providing critical data in biomanufacturing pipelines and molecular biology studies. It is offered in good operational condition but is sold without the associated computer.

This mass spectrometer supports advanced biotechnology applications by enabling *de novo* sequencing and detailed PTM profiling, making it an essential tool for laboratories focused on molecular diagnostics, synthetic biology research, and biomedical engineering workflows.