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Linkam BTL Lyostat 3 Freeze-Drying Microscope System with Trivac D 2.5E Pump, QICAM Camera and Nitrogen Tank

From€19,635excl. VAT

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Specifications 3

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Linkam Scientific Instruments
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Used
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Product description

Freeze-drying microscope system with -196 °C to +350 °C control, vacuum chamber, imaging optics and nitrogen cooling

The Linkam BTL Lyostat 3 freeze-drying microscope system is designed for real-time observation and characterization of freeze-drying processes. It combines controlled temperature and vacuum conditions with optical imaging for research in biopharmaceutical development, formulation science, molecular biology, and pharmaceutical manufacturing.

Temperature and Vacuum Control

  • Working temperature range: -196 °C to +350 °C
  • Controlled heating and cooling rates
  • Programmable temperature profiles with multiple ramping and holding steps
  • High-purity silver heating and cooling block for efficient thermal conductivity
  • 100 ohm platinum resistor sensor, DIN Class A, with control accuracy to 0.1 °C
  • Vacuum-tight sample chamber capable of reaching 10⁻³ mbar
  • Direct chamber-vacuum measurement port
  • Optional vacuum control module
  • Automatic twin-pump liquid nitrogen cooling system with a 2 L Dewar and insulated flexible tubing
  • Direct coolant injection into the silver block

Imaging and Microscope Configuration

The imaging station includes a flip-top head for convenient sample loading, a polarizing lens with analyzer, long-working-distance condenser, and Köhler illumination. The listed microscope configuration includes:

  • Plan 10x objective
  • 1.0x C-Mount video port
  • Widefield 18 mm eyepieces
  • Trinocular head
  • 100 W halogen light source
  • Variable-intensity illumination power supply
  • Olympus microscope stand with Lyostat 3 freeze-drying stage 3MV
  • Olympus U-TAD compensator adapter with U-TP530 530 nm tint compensator
  • Olympus U-LH100L-3 illumination housing with TH4-200 power supply

Software and Control

The system includes a LinkPad controller, Linkam LNP95, and Linkam T95-PE. Software provides live display of temperature, stage pressure, and active ramp information through an RS232 serial connection. Temperature and pressure plots can be viewed, saved, and exported to third-party applications such as Excel. Multi-step temperature profiles can be created using an on-screen data table, while firmware can be upgraded through USB.

Included Hardware

  • Linkam LinkPad Controller
  • Linkam LNP95
  • Linkam T95-PE
  • Linkam Lyostat 3 freeze-drying stage 3MV
  • G16.3 16.3 mm sample carrier
  • Liquid nitrogen D2L container
  • Oerlikon Trivac D 2.5E vacuum pump
  • AF8 exhaust mist filter
  • Edwards LV10K controllable leak valve
  • Q Imaging QICAM 12-bit camera

This freeze-drying microscope is suitable for studying freezing behavior, ice-crystal formation, collapse, eutectic transitions, and other critical events in lyophilization development and biopharmaceutical production pipelines.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 7 November 2026