Fresenius Kabi Cue 6R5000 Automated Closed-Loop Cell Processing System

The Fresenius Kabi Cue 6R5000 is a compact, automated closed-loop cell processing system designed for sterile cell separation, washing, and concentration in regulated cleanroom and clinical environments. It integrates an independent centrifuge, cold plate with active temperature control (3–22°C), and peristaltic pump, enabling precise and reproducible cell processing with minimal manual intervention.

Key technical specifications include:

• Source input volume range from validated 10–500 mL (software permits up to 9,999 mL)
• Minimum final product volume: 10 mL for single aliquots; 2 mL for multiple aliquots
• Volume accuracy: ±10% or 1 mL, whichever is greater
• Protocol versatility: programmable wash, dilute, formulate, concentrate, and aliquot steps with capacity to store 20 protocols on-board.

The system employs sterile, single-use disposable sets for closed sterile processing workflows, critical for applications such as:

• Cell washing and buffy coat isolation
• Red blood cell depletion and plasma removal
• Clinical cell therapy manufacturing, biotechnology bioprocessing, and molecular diagnostics sample preparation
• Workflow automation essential for GMP-compliant biopharmaceutical production pipelines and gene editing research.

Its small footprint and user-friendly interface reduce operator hands-on time while ensuring compliance with clinical and research standards. The Cue 6R5000 is widely adopted in biotechnology and clinical laboratories where reliable, repeatable processing of cellular products is crucial, including synthetic biology, regenerative medicine, and immunotherapy manufacturing.

This system supports robust cell handling protocols used in bioprocessing workflows, live cell processing, and biomedical engineering applications. It is optimized for researchers and clinicians requiring seamless integration of cell processing steps under sterile conditions.

Overall, the Fresenius Kabi Cue 6R5000 represents a technically advanced solution for automated cell separation and processing that streamlines critical workflows in biomanufacturing and molecular biology research environments.