Diagenode Bioruptor Pico Ultrasonic Sonication System for DNA and RNA Shearing

The Diagenode Bioruptor Pico is an ultrasonic bath sonication system designed for reproducible DNA and RNA shearing, chromatin fragmentation, and preparation of biological samples. It uses indirect ultrasonic waves generated by an ultrasonic element beneath the water tank, providing controlled sonication for DNA, protein–protein interactions, protein–DNA complexes, and other biochemical assay systems.

The system supports parallel processing of sealed tubes and continuous tube rotation for improved energy distribution and uniform sample treatment. Automated sonication helps improve repeatability in molecular biology, chromatin immunoprecipitation, next-generation sequencing, molecular diagnostics, and biotechnology workflows.

Technical specifications

• Ultrasonic frequency: 20–60 kHz
• Ultrasonic output power: 25–210 W
• Electrical supply: 100–230 V, 50/60 Hz
• Current: 2.1 A (EU) / 4.2 A (US)
• Sonication unit dimensions: 350 W × 245 D × 280 H mm
• Sonication bath capacity: 750 ml
• Timer: Digital
• Water-flow control through a connection kit for the Bioruptor Cooler: Yes
• Tube holders available for 0.1 ml, 0.65 ml, 1.5 ml, or 15 ml tubes
• Weight: 7.90 kg

Simultaneous sample capacity

• 0.1 ml tubes: 12 samples
• 0.2 ml tubes: 16 samples
• 0.65 ml tubes: 12 samples
• 1.5 ml tubes: 6 samples
• 15 ml tubes: 6 samples

Included

• Diagenode Bioruptor Pico sonication system
• Operating instructions provided as a PDF by email