Bio-Rad iQ-Check Prep System 359-4911 with CFX96 Touch Real-Time PCR Setup Automation

The Bio-Rad iQ-Check Prep System 359-4911 is an advanced automated liquid handling platform designed to streamline DNA extraction and PCR plate preparation workflows, essential for molecular diagnostics and bioprocessing applications. Integrated with the CFX96 Touch Real-Time PCR Detection System, this solution supports multiplex PCR assays with high sensitivity and reproducibility, making it widely adopted in synthetic biology and food pathogen testing laboratories.

Key technical features include:

• Automated liquid handling with SPAN-4 pipetting module, offering precise XYZ positional accuracy of 0.1 mm and variable tip volumes from 50 µL to 1000 µL.
• Dual liquid level detection technologies (capacitive and pressure-based) ensure accurate aspiration and dispensing critical for molecular cloning workflows and gene editing assays.
• Integrated CO-RE grippers and labware carriers enable reliable labware manipulation and plate transfers.
• Hamilton Heater Shaker provides full temperature control and agitation, supporting reaction homogeneity and efficient enzymatic processes in biomanufacturing pipelines.
• 2mag MIXControl MS4 magnetic stirrer with four magnetic stirrer pads enhances reagent mixing precision.
• Honeywell MS7120 Barcode Scanner facilitates sample traceability and integration with Laboratory Information Management Systems (LIMS), crucial for clinical diagnostics and biomedical engineering research.

The CFX96 Touch Real-Time PCR Detection System features:

• Peltier-based thermal cycling with 0–100 °C range, ramp rates up to 5 °C/sec, and ±0.2 °C temperature accuracy for optimal amplification performance.
• Optical system with 6 filtered LEDs and photodiodes detecting excitation/emission wavelengths from 450–730 nm, enabling multiplex fluorescence assays.
• 96-well sample capacity with detection sensitivity down to a single copy of target DNA, supporting quantitative PCR in pathogen detection and synthetic biology research.
• Dynamic range covering 10 orders of magnitude and a scan time of 3–12 seconds per cycle.

This compact, medium-to-high throughput solution integrates fully automated PCR setup, accurate thermal cycling, and multiplex real-time detection, making it critical in food safety testing, molecular biology, and biotechnology research environments. Its design supports seamless workflow integration with existing lab processes without disruption.

Ideal applications include:

• Routine foodborne pathogen detection (Salmonella, Listeria, E. coli) in quality assurance labs.
• High-throughput sample processing for PCR-based genomic assays.
• Automated DNA extraction and PCR plate preparation facilitating biopharmaceutical production pipelines and molecular cloning workflows.

This system also includes essential peripherals, software (Bio-Rad iQ-Check Prep v4.1.9), and comprehensive warranty with technical support, remote training options, and tested functionality ensured by in-house service teams. Its robust design and extensive validation make it a reliable choice for researchers focused on molecular diagnostics, synthetic biology, and biotechnology-driven methodologies.