Agilent AssayMAP Bravo Protein Sample Prep Platform Liquid Handler with 96LT Dispense Head

The Agilent AssayMAP Bravo Protein Sample Prep Platform is a modular, automated liquid handling workstation designed to deliver precise, reproducible protein and peptide sample preparation for applications such as LC-MS, biomarker discovery, and phosphoproteomics. Featuring dual dispense heads—AssayMAP cartridge-based and 96LT plate-based—this system supports parallel processing of complex sample preparation protocols, including automated aspiration, dispensing, washing, and reagent handling with high positional accuracy.

Key Features and Specifications:

• Automated 96-channel liquid handling optimized for high-throughput plate-based workflows in proteomics and molecular diagnostics.
• Precision low-volume dispensing via AssayMAP and 96LT dispense heads, essential for sensitive biomolecular assays.
• Integrated gripper arm for automated plate transport and positioning, enhancing workflow automation and reducing manual handling.
• On-deck thermal control modules: Inheco Single TEC and CPAC Ultraflat HT 2-TEC, enabling temperature profiling from 4 °C to 110 °C for enzymatic digestion, protein purification, or thermal cycling.
• Shaking capability through Thermo Teleshake and Shakemodul for incubation or mixing steps critical in sample prep workflows.
• Automated washing station (Agilent 96AM Wash) and Pump Module 2.0 for reagent delivery and waste management.
• Enclosed benchtop design with safety interlocks including a light curtain and emergency stop for unattended operation.
• Flexible deck configuration with six standard plate pads and riser feet, customizable with magnetic extraction, vacuum modules, or thermal cyclers for advanced assay development.
• PC-based system control via VWorks software for scheduling, method programming, and data logging.
• Comprehensive customization options to adapt to specific protein purification workflows like Protein A/G purification, trypsin digestion, IMAC phosphoproteomics enrichment, and glycoprotein enrichment with lectin cartridges.
• Supported by extended warranty, preventive maintenance, volume verification (Artel MVS), and technical consultation to ensure integrity and reproducibility in biotechnology and molecular biology research pipelines.

Applications:

• Protein and peptide sample preparation for LC-MS proteomics analysis
• High-throughput antibody purification and characterization workflows
• Glycan analysis and post-translational modification enrichment
• Biomarker discovery and phosphopeptide enrichment protocols
• Versatile platform widely adopted in synthetic biology research and critical in biopharmaceutical production pipelines

This platform is essential for molecular cloning workflows, enabling reliable automation of repetitive liquid handling tasks to improve throughput and consistency in biotechnology labs focused on molecular diagnostics and bioprocessing.

Keywords: automated liquid handling system, protein sample preparation, Agilent Bravo, AssayMAP dispense head, LC-MS sample prep, high-throughput liquid handler, proteomics automation, biomarker discovery, phosphoproteomics, biomanufacturing, synthetic biology research, molecular diagnostics, plate-based liquid handler, benchtop liquid handling workstation.