BioDot RR120 Modular Web Handling System with BioJet/AirJet Dispensing and Vision Inspection

The BioDot RR120 Modular Web Handling System is designed for precision roll-to-roll processing of membrane-based substrates, widely used in biotechnology, molecular diagnostics, and bioprocessing workflows. This integrated platform combines non-contact BioJet and AirJet liquid dispensing technologies with a high-resolution Keyence CA-H048MX in-line vision system for optimized quality control and process monitoring.

Key features include:

• Roll-to-roll web handling supporting membrane widths from 5 mm to 120 mm and adjustable speeds up to 100 mm/sec, critical for continuous membrane coating and lateral flow assay manufacturing.
• Dispensing modules: four BioJet dispensers with solenoid valve microvalves enabling volumetric precision (2.6 nL to 2.0 µL per drop) for antibody lines, nanoparticles, and buffer solutions; three AirJet dispensers deliver controlled, pneumatic reagent lines with droplet volumes from 0.1 to 24 µL/cm for reagent coating applications.
• Vision inspection: Keyence 5 MP monochrome camera with an 8 mm f/1.4 lens facilitates real-time edge detection, line width tolerance monitoring, and dot/line placement alerts to ensure critical alignment and product consistency in biosensor strip production.
• Dual drying towers, each with three independently controlled IR-heated zones (ambient to 70°C), ensure uniform solvent evaporation and reagent stabilization critical for biopharmaceutical membrane processing.
• Web tension control and stability are managed with a servo motor-driven capstan module with encoder feedback, passive brake payout reel, and motorized takeup reel, enabling ultra-low to moderate tension regimes suitable for delicate or laminated membranes.
• Additional modules include a programmable dipping tank for immersion coating with level sensing and a marker system triggered by vision alerts for defect identification.

This modular system is essential for biomanufacturing workflows requiring high-throughput, precise reagent dispensing and coating, such as lateral flow assay production, protein/antibody line dispensing, and biosensor fabrication. Its integrated vision system and multi-zone drying capacity make it critical in maintaining manufacturing quality standards in synthetic biology and molecular cloning workflows. The system supports continuous, automated processing compatible with aqueous and organic solvent reagents, making it a valuable asset in biomedical engineering applications focused on membrane functionalization and diagnostic assay assembly.

The BioDot RR120 is widely adopted in laboratories engaged with cell imaging substrates, clinical diagnostics, and bioprocess reagent preparation, offering robust, reproducible, and scalable roll-to-roll membrane processing essential for modern biotechnology research and production environments.