Olympus IX81 Inverted Fluorescence Motorized Microscope with Automated Z-Axis and Filter Turret

The Olympus IX81 Inverted Fluorescence Motorized Microscope is a high-performance system designed for advanced life science and biotechnology applications such as molecular diagnostics, gene editing, and synthetic biology research. This fully motorized inverted microscope supports brightfield and fluorescence microscopy with automated control of both the Z-axis focus, filter cube turret, and objective nosepiece turret, enabling precise multiparametric imaging essential for live cell imaging and time-lapse studies.

Key features include:

• Automated motorized Z-axis drive for autofocus, parfocality adjustment, and recall of saved focus positions, critical for high-throughput bioprocessing workflows.
• Motorized 6-position fluorescence filter cube turret loaded with three brand new filter sets including DAPI, FITC/EGFP, TRITC/Cy3, Texas Red, and Cy5 compatible filters, ensuring optimal excitation and emission efficiency for a broad range of fluorochromes used in molecular biology and fluorescence analysis.
• Motorized 6-position objective turret equipped with Olympus UplanFL objectives (4x, 10x, 20x, 40x) suitable for magnifications from 40x to 1000x with 10x eyepieces, supporting detailed cellular and subcellular imaging.
• Brightfield illumination via Olympus 100 W halogen light source integrated into the base, alongside an Olympus fluorescence light path powered by an EXFO 120 metal halide illumination system, optimized for stable, high-intensity fluorescence excitation.
• Mechanical XY stage with optional motorized upgrade for multi-position imaging, ideal for complex experiments involving sample mosaics or multi-well plates used in biopharmaceutical production pipelines.
• High-resolution 8.3 MP CMOS color camera (Bestscope) integrated with open-source Micromanager and ImageJ software suite enabling advanced multi-dimensional image acquisition and analysis including time lapse, Z stacking, and multi-position stitching.

The Olympus IX81 supports various microscopy techniques and customizations such as phase contrast, differential interference contrast (DIC), polarization, additional fluorescence filters, and upgraded illumination sources (LED, xenon), adaptable to diverse requirements in cell biology, developmental biology, neuroscience, and clinical diagnostics.

This inverted fluorescence microscope system is especially suited for biotechnological workflows involving genetic engineering, live-cell imaging, and synthetic biology due to its precise automation features and flexible fluorescence capability. Its predecessor to the IXplore IX85 offers excellent performance at reduced investment, making it a popular choice among molecular biology researchers and bioprocess engineers seeking reliable, high-throughput microscopy solutions.

Technical specifications at a glance:

• Fluorescence filter sets: DAPI (EX 365/28 nm, EM 445/50 nm), EGFP/FITC (EX 475/30 nm, EM 530/40 nm), TRITC/Cy3 (EX 545/20 nm, EM 605/60 nm), Texas Red, Cy5
• Objectives: UplanFL 4x, 10x, 20x, 40x
• Illumination: EXFO 120 metal halide fluorescence, Olympus 100W halogen brightfield
• Motorized features: Z-axis, filter turret, objectives turret
• Imaging: 8.3 MP color CMOS camera, Micromanager/ImageJ support
• Applications: Live cell imaging, fluorescence analysis, time-lapse microscopy, molecular diagnostics, biotechnology research, drug discovery

This microscope is delivered fully serviced with preventive maintenance completed, optical path calibration, fluorescence intensity verification, and comes with a 180-day USA and 60-day international warranty, with optional extended warranties and remote training available. Ideal for university research labs, biopharma R&D, and clinical diagnostic settings, the Olympus IX81 offers a robust and flexible platform for advanced fluorescence microscopy and live-cell imaging experiments essential in modern biotechnology and biomedical engineering.