Olympus BX53 Fluorescence Motorized Upright Microscope with Motorized XY Stage and New Fluorescence Filters

The Olympus BX53 Fluorescence Motorized XY Microscope is a research-grade upright microscope designed for advanced fluorescence and brightfield imaging applications critical in cell biology, molecular diagnostics, and biotechnology workflows such as live-cell imaging and immunofluorescence. This modular system features a U-TR30 trinocular head equipped with WH10x/22 eyepieces and a camera port, facilitating simultaneous visual and digital imaging.

Key technical specifications include:

• Fluorescence illumination via an EXFO X-Cite 120 120W metal halide lamp, optimized for high-intensity excitation in various fluorochrome channels.
• A 6-position mechanical fluorescence filter turret loaded with any three new filter sets from DAPI, FITC/EGFP, TRITC/Cy3, Texas Red, and Cy5, enabling multiplexed fluorescence detection essential for bioprocessing and synthetic biology analyses.
• Brightfield illumination accomplished with LED or halogen light sources capable of histology and pathology slide examination.
• Objectives mounted on a 6-position mechanical nosepiece include 4x/0.13, 10x/0.30, and 20x/0.50 UPlanFL lenses, with options to upgrade up to 1000x magnification for high-resolution imaging.
• A Marzhauser motorized XY stage equipped with MCX-2 eco control box and joystick for precision sample navigation, critical in multi-slide scanning and microplate assays.
• Imaging capture and analysis supported by an 8.3MP Bestscope color CMOS camera and ImageJ software, allowing live video, still image acquisition, annotation, calibration, and quantitative measurements aligned with biomedical engineering and molecular diagnostics workflows.

Additional configurable options allow customization with phase contrast, DIC, and polarization modules, higher-performance objective lenses, advanced CCD/sCMOS/EMCCD cameras, and upgraded fluorescence light sources such as Lumencor LEDs. System calibration and preventive maintenance ensure verified optical performance, fluorescence intensity checks, mechanical lubrication, and smooth stage movement, supporting demanding research in neuroscience, cancer biomarker studies, and plant fluorescence analysis.

The Olympus BX53 is widely adopted in academic and biopharma laboratories, providing a robust platform for advanced fluorescence microscopy, live-cell imaging, quantitative fluorescence analysis, and essential molecular biology research techniques. The system is backed by a 180-day warranty in the continental USA, remote training support, and customizable service agreements—making it suitable for precision-driven synthetic biology research, cell imaging workflows, and biomanufacturing monitoring.

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