Leica DM6 B Upright Motorized Fluorescence Microscope with Trinocular Head and 8.3MP CMOS Camera

The Leica DM6 B Upright Fluorescence Microscope is a motorized, high-precision research instrument designed for advanced fluorescence imaging applications in biotechnology and biomedical fields. It features:

• Optical and Mechanical Configuration:
• Upright microscope base with motorized 8-position objective turret supporting 4x, 10x, and 20x PL Fluotar objectives
• Trinocular head with camera port and dual eyepieces
• Mechanical XY stage and mechanical condenser for precise specimen positioning and illumination

• Fluorescence Imaging System:
• EXFO X-Cite 120 Metal Halide fluorescence light source with collimating adapter and light guide
• Motorized 5-position fluorescence filter cube turret loaded with three filter cubes, compatible with various fluorochromes for multiplexed fluorescence analysis
• Motorized fluorescence shutter and adjustable light intensity for controlled illumination to minimize photobleaching

• Brightfield Illumination:
• Leica 100 Watt halogen light source with motorized aperture and field diaphragm controls for brightfield microscopy techniques

• Automation and Motorization:
• Motorized Z-axis drive enabling automated parfocality adjustment, programmable focus recall, and fine-coarse positioning essential for multi-slice (Z-stack) and time-lapse imaging in live-cell and molecular biology studies
• Motorized objective and filter cube turrets for rapid configuration changes
• Camera port configuration options with up to 100% light directed to imaging sensor

• Imaging and Software Capabilities:
• Integrated Bestscope 8.3MP color CMOS camera with 1x C-mount adapter for high-resolution color imaging
• Dell laptop with Windows 10 and open-source Micro-Manager software for comprehensive live image acquisition, annotation, multi-dimensional (time-lapse, Z-stack, stitching) image analysis, and processing
• Supports quantitative fluorescence image analysis and measurement, critical for molecular diagnostics and bioprocessing research

• Customization and Upgrades:
• Optional add-ons include phase contrast, DIC, polarization modules, higher magnification objectives (up to 200x with 10x eyepieces), advanced CCD/sCMOS/EMCCD cameras, and upgraded LED or Xenon fluorescence light sources
• Compatibility with diverse sample formats such as slides, Petri dishes, and microplates, enhancing versatility in cell imaging and biotechnology workflows

• Applications:

This microscope is extensively used in:

• Molecular biology and synthetic biology for fluorescent labeling and gene editing research
• Biopharmaceutical production pipelines requiring high-resolution live-cell observation and multi-dimensional quantitative analysis
• Neuroscience, cell imaging, pharmacology, and materials science research demanding robust fluorescence and brightfield capabilities

• Service and Support:
• Fully serviced with preventive maintenance completed, including optics quality validation for field uniformity and fluorescence intensity
• Includes 180-day USA warranty and 60-day international warranty
• Remote training sessions on both hardware operation and image analysis software to facilitate rapid integration into research workflows
• Expert consultation to customize microscope configuration tailored to user-specific research needs

This Leica DM6 B fluorescence microscope combines precision motorized controls, advanced optics, and versatile imaging modalities, making it an essential instrument for biotechnology researchers involved in molecular diagnostics, live-cell fluorescence imaging, and quantitative microscopy. Its automation features support complex multi-dimensional imaging critical to cutting-edge bioprocessing and synthetic biology applications.