Buchi Sepacore Flash Chromatography System with C-660 Fraction Collector, C-601 Pump, C-615 Pump Manager, and C-635 UV-Vis Detector

The Buchi Sepacore Flash Chromatography System integrates advanced modules optimized for precise compound separation and collection in biotechnological and chemical research workflows, including molecular diagnostics and synthetic biology applications.

• Fraction Collector C-660
• Enables programmable compound collection based on time, volume, or peak mode
• Compatible with various tube and vessel types for flexible sample handling
• Ensures high precision through adjustable delay times
• Pump Module C-601 + Pump Manager C-615
• Manages dual-pump flow rates with real-time pressure monitoring up to 50 bar (maximum pressure per pump 10 bar / 145 psi)
• Achieves pulse-free solvent delivery via 3-piston pump head technology
• Supports flow rates up to 250 mL/min within a compact footprint
• Critical for reproducible gradient formation essential in bioprocessing and molecular cloning workflows
• UV-Vis Detector C-635 (UV Photometer)
• Detects compounds across a broad wavelength range of 190–740 nm, enabling comprehensive spectral analysis
• Simultaneous monitoring of up to four wavelengths improves detection efficiency for complex samples
• Features deuterium discharge and halogen light sources for stable baseline and spectral accuracy (±1 nm)
• Interfaces via RS232 for seamless integration with SepacoreControl software enabling UV-Vis scans in real-time

This modular flash chromatography system is widely adopted in synthetic biology research and biopharmaceutical production pipelines, supporting critical workflows such as purification of nucleic acids, peptides, and small molecules. Its precise fraction collection and reliable solvent delivery streamline biomanufacturing and molecular diagnostics applications, making it a robust choice for research laboratories engaged in advanced biotechnology and chemical synthesis.