Advion Interchim PuriFlash 5.015 XL Preparative Flash Purification System with Integrated UV Detection and Automated Fraction Collection

The Advion Interchim PuriFlash 5.015 XL is a high-capacity preparative flash purification system designed for large-scale purification workflows in research, pilot, and production laboratories. It supports scalable compound isolation, ranging from multi-gram to kilogram quantities, making it essential for molecular diagnostics, bioprocessing, and biomanufacturing applications in biotechnology and chemical synthesis.

Key technical features include:

• Flow rate range: 1–825 mL/min with ±2.5% accuracy between 100–750 mL/min at 5–12 bar pressure
• Maximum operating pressure: 15 bar (217 psi) suitable for robust preparative separations
• Quaternary gradient valve with gradient tolerance step <3.5% enabling precise solvent mixing and gradient elution
• Injection: Manual liquid or solid sample injection compatible with diverse preparative workflows
• UV Detection: Diode Array Detector (DAD) technology covering 200–400 nm wavelength range for real-time compound monitoring and purity assessment
• Fraction collector capacity: Automated collection with 3 racks holding up to 132 samples (44 tubes per rack, 25 mL per tube), improving reproducibility and throughput
• System components: Includes PuriFlash 5.015-UC control unit with InterSoft X software, PuriFlash pump, fraction collector, integrated dry-load and column holders, and solvent tray with drainage system

Applications encompass preparative purification of organic compounds, synthetic intermediates isolation, and kilo-lab scale separations critical in synthetic biology and biopharmaceutical production pipelines. The system’s high flow rate and large column format support bioprocessing requirements and scalable chromatography workflows widely adopted in molecular cloning and gene editing research.

Additional customization options include expanded fraction collection racks and compatible C18 preparative columns for enhanced selectivity and resolution.

This system undergoes rigorous in-house testing to validate solvent valve operation, pump flow accuracy, gradient performance, UV detector sensitivity (verified with caffeine peak detection), and fraction collector functionality, ensuring reliable and fully functional performance upon delivery.

Optimal for scientists, researchers, and laboratory buyers focused on preparative chromatography in biotechnology, medicinal chemistry, and chemical biology, this system integrates essential features for efficient and reproducible large-scale compound purification.