X-Cite XYLIS II LED Fluorescence Light Source for Compound & Stereo Microscopes (XT730S/XT730L)

The X-Cite XYLIS II by Excelitas Technologies is a high-performance LED fluorescence light source designed for *compound* and *stereo microscopes*, providing broad-spectrum excitation from 360 nm to 770 nm covering fluorophores from *DAPI* to *Cy7*. This instrument employs patented LaserLED Hybrid Drive® technology to deliver continuous high-intensity illumination with spectral peaks at 365/385, 430, 475, 545, 635, and 735 nm, supporting a comprehensive range of fluorophores relevant to biotechnology and molecular diagnostics.

Available in two models:

• XT730S with 365 nm UV excitation, compatible with standard DAPI filter sets
• XT730L with 385 nm UV excitation, optimized for specific fluorescence applications

Both models feature a liquid-light-guide output for efficient light transmission and multiple control interfaces including manual speedDIAL, TTL, USB, and an optional foot pedal, enabling seamless integration into automated fluorescence imaging workflows. The system achieves brightness comparable to traditional arc lamps but offers superior instant ON/OFF switching, low maintenance, and a notably long LED lifespan (~25,000 hours), eliminating the need for frequent bulb replacements and reducing operational costs.

Engineered for quiet laboratory environments, the XYLIS II operates at approximately 10 dB quieter than its predecessor, enhancing usability in multi-user microscopy suites and biomanufacturing facilities. Its fast switching speeds (100 µs TTL, 1 ms USB) make it well-suited for time-lapse imaging, live-cell fluorescence microscopy, immunofluorescence assays, and multicolor staining protocols—applications widely used in synthetic biology, molecular cloning workflows, and advanced biomedical research.

Key features:

• Broad-spectrum LED excitation spanning 360–770 nm for diverse fluorophore compatibility
• UV excitation choices: 365 nm (XT730S) or 385 nm (XT730L) to match classic DAPI filters
• High optical output rivaling arc lamps without mercury or bulb replacements
• Instant ON/OFF with rapid TTL/USB switching, ideal for dynamic fluorescence experiments
• Flexible control: manual speedDIAL, foot pedal, TTL, USB for automated imaging systems
• Quiet operation (~10 dB noise reduction) suitable for shared microscopy labs
• Long-lasting LEDs (~25,000 hours) with stable output and reduced energy consumption

This LED fluorescence light source is essential for researchers in molecular biology, biotechnology, and clinical diagnostics requiring reliable and versatile illumination for advanced microscopy, including FISH, live-cell imaging, and complex multicolor fluorescence analysis.