Leica Aperio GT450 High-Capacity Digital Slide Scanner for Histology and Pathology Imaging

The Leica Aperio GT450 Digital Slide Scanner is a specialized instrument designed for high-throughput digitization of histology and pathology slides, widely used in clinical diagnostics, cancer research, toxicology, and drug discovery. This automated digital slide scanner enables rapid whole-slide imaging with precise optical resolution and robust sample handling capabilities essential for molecular diagnostics and bioprocessing workflows.

_Key technical specifications include:_

• Maximum Slide Capacity: 450 slides with continuous rack loading
• Rack Compatibility: Fits 15 racks of 30 slides or 15 racks of 20 slides, providing flexible workflow integration for large sample volumes
• Optical Magnification: 20x and 40x objectives available for detailed cellular and tissue imaging
• Image Resolution: 0.26 μm per pixel at 40x magnification, delivering high-definition digital images suitable for quantitative image analysis in biotechnology and synthetic biology research
• Scanning Speed: Approximately 32 seconds to scan a 15 × 15 mm area at 40x, enabling a throughput of up to 81 slides per hour, which supports biopharmaceutical production pipelines requiring efficient data acquisition
• Field of View (FOV): 1 mm with default calibration point and automated narrow stripe scanning for consistent image quality
• Barcode Reader: Supports both 1D and 2D symbology for slide tracking and sample traceability in clinical laboratory information management systems (LIMS)
• Slide Size Supported: Standard 1 × 3 inch microscopy slides compatible with most pathology workflows
• Physical Dimensions: 20.8" (W) × 28" (D) × 19.5" (H), weight approximately 140 lbs (63.5 kg)

The scanner includes an automated image quality check and priority rack scanning features designed to maximize throughput efficiency. It is critical in biotechnological applications involving gene editing, molecular cloning, and histopathological analysis, ensuring accurate digital archiving and facilitating telepathology consultations.

Note that this unit is sold as-is, untested, without warranty or software support, and Leica no longer provides service for the GT450 model. Despite this, it remains a high-capacity solution for institutions capable of integrating legacy equipment into existing digital pathology infrastructures.

This scanner is essential for labs prioritizing large-scale slide digitization for live-cell imaging, fluorescence analysis, and biomedical engineering applications. Its high capacity and speed align with the demands of synthetic biology research groups requiring high-resolution histological image data.

For shipment, instruments are securely packed in ISPM15-certified wooden crates with shock and tilt indicators, ensuring safe delivery. Technical consultation and demonstration options are available for pre-owned instrument acquisition, ideal for academic and biopharmaceutical laboratory environments focused on molecular diagnostics and biomanufacturing advancements.