Metrohm 645 Multi-Dosimat with 633 Automat Controller for Precise Karl Fischer Titration

The Metrohm 645 Multi-Dosimat combined with the 633 Automat Karl Fischer Titrator provides a reliable, precise dosing and titration platform widely used in chemical analysis and molecular diagnostics laboratories. This system specializes in accurate volumetric dosing of liquids and flammable solvents, essential for applications such as bioprocessing quality control, industrial chemical analysis, and molecular biology workflows requiring precise water content determination.

Key features include:

• Multi-Dosimat 645: delivers precise dosing of reagents with high reproducibility; ideal for titrant addition in Karl Fischer titrations.
• 633 Automat controller: automates endpoint detection and titration processes; increases throughput and reduces manual error.
• Compatible with E649 stirrer stand and 10 mL exchange units to ensure consistent sample mixing and reagent exchange.
• Use of adsorbing-drying tubes (P/N 6.1609.000) improves measurement quality by removing moisture from reagents or air, critical for sensitive molecular diagnostics and synthetic biology research requiring stringent moisture control.
• Commonly employed in biotechnology laboratories for moisture determination in biopharmaceutical raw materials, excipients, and final products.

This setup is essential in biomanufacturing and quality assurance pipelines, facilitating precise water content analysis critical for stability and formulation in cell imaging reagents, nucleic acid preparations, and synthetic biology compounds. Note: the unit is sold as-is, powers on, but full functional testing was not completed. Spare adsorbing-drying tubes are optionally available to maintain performance standards.

This Karl Fischer titrator system is a fundamental instrument for scientists and researchers requiring automated, volumetric titration combined with accurate dosing—widely adopted in clinical diagnostics and environmental testing applications.