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Procurable · sourced on request

Malvern Panalytical MicroCal iTC200

UsedMalvern PanalyticalSample preparationNetherlands
Procurable

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Sample Volume
10 µg
Cell Volume
200 µL
Injection Syringe Volume
40 µL
Cell Material
Hastelloy
Cell Shape
Coin-shaped
Availability
Procurable
Lead time
Confirmed with your quote
All 18 specifications
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Specifications 18

Brands
Malvern Panalytical
New/Used
Used
Sample Volume
10 µg
Cell Volume
200 µL
Injection Syringe Volume
40 µL
Cell Material
Hastelloy
Cell Shape
Coin-shaped
Affinity Range
10^-2 to 10^-9 M
Dissociation Constant Range
10^-9 to 10^-12 M
Temperature Range
2°C to 80°C
Temperature Stability
±0.00012°C
Operating Temperature Range
10°C to 28°C
Operating Humidity Range
0% to 70% RH, non-condensing
Injection Volume Precision
<1% at 2 µL
Response Time
10 s
Noise Level
0.15 ncal/s
Availability
Procurable
Lead time
Confirmed with your quote

Product description

Sensitive low-volume ITC for direct biomolecular interaction analysis with detailed thermodynamic data.

MicroCal iTC200 is a highly sensitive, low-volume isothermal titration calorimeter (ITC) designed for the direct, label-free analysis of biomolecular interactions. This instrument measures the heat released or absorbed during binding events, providing comprehensive data on binding affinity (K<sub>D</sub>), stoichiometry (n), enthalpy (ΔH), and entropy (ΔS) in a single experiment.

Key features include:

  • Minimal sample requirements: Utilises as little as 10 µg of protein, conserving precious samples.
  • Wide affinity range: Directly measures millimolar to nanomolar affinities (10<sup>-2</sup> to 10<sup>-9</sup> M) and, using competitive binding techniques, can assess nanomolar to picomolar dissociation constants (10<sup>-9</sup> to 10<sup>-12</sup> M).
  • User-friendly software: Facilitates fast and accurate analysis with minimal assay development, requiring no labelling or immobilisation.
  • Upgradeable to automation: Can be upgraded to the fully automated MicroCal Auto-iTC200, enhancing productivity for higher workloads.

This system is widely applied in biotechnology, pharmaceutical research, and molecular biology, particularly in drug discovery, protein engineering, and bioprocessing. It is commonly utilised in university laboratories, biomedical research centres, and biopharmaceutical companies.

The MicroCal iTC200 was first released in 2007 and has been a valuable tool in the scientific community since then.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 10 November 2026