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High-purity HPA-12 inhibits ceramide transport, aiding sphingolipid metabolism and cellular signaling studies.
HPA-12 is a potent inhibitor of ceramide trafficking, playing a crucial role in sphingolipid metabolism research. By impeding the transport of ceramide from the endoplasmic reticulum to the Golgi apparatus, this compound aids in elucidating the mechanisms underlying sphingomyelin synthesis and its implications in various biological processes.
First reported in 2001, HPA-12 remains a valuable tool in lipid research, contributing to advancements in understanding sphingolipid-related diseases and the development of novel therapeutic strategies.
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We're an independent team based in The Netherlands, working with research labs and procurement teams across Europe and worldwide.
With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.
Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.
Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.
Two to six weeks, depending on refurbishment scope and whether calibration is included.
We ship to 38 countries. Crating and customs handling are quoted with the instrument.
Tell us what you need and a scientist finds it for you, usually within the hour.
Last updated 28 October 2026
