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Potent, selective MEK1/2 inhibitor with >98% purity, soluble to 75 mM in DMSO for cell signaling studies.
Calbiochem PD98059 is a potent, cell-permeable inhibitor of MEK1/2 (mitogen-activated protein kinase kinase 1 and 2), effectively blocking the activation of the MAPK/ERK signalling pathway. This inhibition is crucial for researchers investigating cellular processes such as proliferation, differentiation, and survival.
Key features include:
PD98059 is widely utilised in:
Commonly employed in:
First introduced in the mid-1990s, PD98059 remains a valuable tool in scientific research, particularly in the biotechnology sector, for elucidating complex signalling pathways and developing targeted therapies.
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We're an independent team based in The Netherlands, working with research labs and procurement teams across Europe and worldwide.
With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.
Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.
Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.
Two to six weeks, depending on refurbishment scope and whether calibration is included.
We ship to 38 countries. Crating and customs handling are quoted with the instrument.
Tell us what you need and a scientist finds it for you, usually within the hour.
Last updated 4 November 2026