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Miltenyi Biotec CliniMACS Prodigy Automated Cell Processing System for GMP Cell Manufacturing

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Pump Speed
2-400 ml/min
Atmosphere control
Gas mix unit for CO2, compressed air, and N2; min. pressure: 1 bar, max. pressure: 2.5 bar
Temperature Control
4°C to 38°C
Centrifugation
Up to 2500 rpm (400 x g)
Microscope Camera
Up to 400x
All 16 specifications
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Specifications 16

Brands
Miltenyi Biotec
New/Used
Used
Pump Speed
2-400 ml/min
Atmosphere control
Gas mix unit for CO2, compressed air, and N2; min. pressure: 1 bar, max. pressure: 2.5 bar
Temperature Control
4°C to 38°C
Centrifugation
Up to 2500 rpm (400 x g)
Microscope Camera
Up to 400x
Display/Controls
Full color, 10.1” TFT touchscreen
MACS tube sealer
For sealing CliniMACS Prodigy Tubing Sets PVC Tubes
Types of starting material
Leukapheresis, bone marrow, cryopreserved PSCs
Available cell processing steps
Cell washing, density gradient centrifugation, cell activation, fluorescent antibody labeling of cells, cell depletion and / or enrichment via magnetic cell separation, viral transduction, cell expansion, expansion and differentiation of adherent cells, cell culture and medium exchange, formulation of final cell product
IPC/QC
Integrated IPC/QC sampling pouches allow sterile sample removal
Manufactured in
Germany
Dimensions
29x16x19”
Weight
155 lbs
Electrical
100-240V, 50/60Hz, 810VA

Product description

Automated closed-system for cell processing with magnetic separation, expansion, and gene modification capabilities.

The Miltenyi Biotec CliniMACS Prodigy Automated Cell Processing System is a compact, closed-system platform designed to automate complex cell manufacturing workflows essential for molecular diagnostics, gene therapy, and bioprocessing. Engineered for compliance with GMP standards, this instrument integrates multiple cell processing steps including:

  • Magnetic cell separation for T cells, NK cells, and stem cells using the magnetic separation column
  • Automated cell washing, density gradient centrifugation, and cell activation within a temperature-controlled CentriCult Unit (4°C to 38°C)
  • Genetic modification via viral transduction and fluorescent antibody labeling for in-depth cell characterization
  • Cell expansion and differentiation, supporting both suspension and adherent cell cultures
  • Integrated IPC/QC sampling pouches for sterile sample removal ensuring process validation
  • Precision fluid handling via a peristaltic pump operating between 2-400 ml/min with pinch valves controlling fluid paths
  • Gas mix unit providing controlled atmosphere with CO2, compressed air, and N2 for optimal cell cultivation conditions

The system’s 10.1” full-color touchscreen controller includes preinstalled software supporting over 300 customizable protocols currently utilized in more than 150 clinical trials. This allows scientists and biotechnology professionals to streamline workflows, minimize human error, and scale processes from research-grade cell sorting to commercial biomanufacturing.

Additional technical specifications: centrifugation up to 2500 rpm (400 x g), microscope camera magnification up to 400x, and compatibility with starting materials such as leukapheresis, bone marrow, and cryopreserved pluripotent stem cells. The device supports seamless network connectivity for data export and remote monitoring, integrating with laboratory information management systems common in biomedical engineering and cell therapy manufacturing.

Manufactured in Germany, the CliniMACS Prodigy measures 29x16x19 inches, weighs 155 lbs, and operates on 100-240V, 50/60Hz power supplies. It is widely recognized in synthetic biology research and cellular immunotherapy development as a critical tool for standardized cell processing and manufacturing of clinical-grade cell products.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Yes. Every verified supplier states which service partners cover the instrument, and we list that alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 19 October 2026