Cytiva Xuri W25 Automated Cell Expansion Bioreactor System for Cell Therapy

The Cytiva Xuri W25 Cell Expansion Bioreactor System is an automated, controlled environment platform designed for efficient expansion of cell therapies up to 25 L volume, supporting applications in research, process development, and biomanufacturing. This closed, single-use bioreactor system enables high-density cell culture (>10 x 10^6 cells/mL) under low-shear conditions, critical for delicate mammalian and stem cell expansions in molecular diagnostics and synthetic biology workflows.

Key system features include:

• Automated perfusion protocols for sustained cell growth and metabolic control.
• Non-invasive rocking motion with adjustable speed (2 to 40 rpm) and angle (2° to 12°) to optimize mixing and oxygen transfer.
• Integrated environmental control with precise regulation of temperature (±0.2°C accuracy, 2°C–40°C control range), pH (6.0–8.0 control range), dissolved oxygen (0%–100% air saturation control), and CO2 (0%–15%) levels, ensuring optimal culture conditions for biotechnology applications including gene editing and bioprocessing.
• Remote operation and monitoring facilitated by UNICORN software, enabling advanced control capabilities and real-time data access essential for GMP-compliant manufacturing.
• Gas supply specifications with independent adjustment of air, CO2, and O2 flows to maintain optimal metabolic conditions.
• Precise peristaltic pump system with flow rates from 0.07 to 100 mL/min and ±10% volume accuracy, supporting perfusion with customizable tubing dimensions.
• Compact modular components: rocker unit, control box (CBCU), and pump module for flexible installation and scalability.

This bioreactor system is widely adopted in cell therapy manufacturing pipelines, biopharmaceutical production, and synthetic biology research, ensuring contamination risk is minimized through its closed design. Its robust monitoring and control make it essential for molecular cloning workflows and live-cell expansion processes that require stringent environment stability and performance.