Cytiva GE Xuri W25 Cell Expansion System with Tray 10 for Controlled Single-Use Cell Culture Expansion

The Cytiva GE Xuri W25 Cell Expansion System w/ Tray 10 is a sophisticated rocking bioreactor designed for scalable suspension cell culture and expansion workflows, widely used in biotechnology and molecular diagnostics. This single-use bioreactor system supports working volumes from 300 mL to 5 L using Cellbag bioreactors (2 L and 10 L sizes). It delivers precise control of temperature (2–50°C), pH (4.5–8.5), dissolved oxygen (DO), and gas mixing (CO₂ 0–15%, O₂ 0–50%), essential for reproducible upstream bioprocess development, CAR-T and T-cell manufacturing, vaccine production, and stem cell expansion.

Key system components include:

• Xuri W25 Rocker Unit with adjustable rocking speed (2–40 rpm) and angle (2°–12°) for efficient mixing and gas transfer.
• W25 CBCU (Cellbag Control Unit) for comprehensive process control of gas flow (50–1000 mL/min), pH, and DO sensors.
• Xuri W25 Pump, a peristaltic pump delivering flow rates between 0.1 to 144 L/day (0.07–100 mL/min), enabling flexible media feeding or perfusion strategies.
• Integrated computer with Unicorn software v7.6 for real-time monitoring and control.

The system is configured for single Cellbag operation on Tray 10 but can be upgraded for dual-bag workflows, supporting perfusion-based cell culture processes critical in biomanufacturing and synthetic biology applications. This compact system is optimized for laboratory-scale bioprocessing, providing stable and reproducible culture conditions, making it highly suitable for academic, clinical, and industrial research environments.

Extensive functional testing confirms operational reliability, including pump functionality, gas flow stability, temperature uniformity, sensor calibration, and safety interlock functionality. Users must acquire external consumables such as Cellbag bioreactors and tubing sets separately.

This platform is widely adopted for biotechnology and molecular biology research, particularly in gene editing and cell therapy bioprocess pipelines. The precise environmental control enhances live-cell culture results, essential for high-quality, scalable cell expansion. Keywords: rocking bioreactor system, single-use bioreactor, controlled cell expansion system, upstream bioprocess, biotechnology cell culture, CAR-T manufacturing, stem cell expansion, molecular diagnostics bioprocessing, perfusion culture system, biomanufacturing equipment.