Leica BOND-III Fully Automated IHC and ISH Slide Staining System with 30-Slide Capacity

The Leica BOND-III is a fully automated benchtop staining system engineered specifically for high-throughput research in immunohistochemistry (IHC) and in situ hybridization (ISH) applications, critical in molecular diagnostics and biotechnology research workflows. It supports continuous processing of up to 30 slides simultaneously via three independent trays, enabling uninterrupted slide preparation and efficient workflow in tissue biomarker detection and genetic analysis.

Key Technical Specifications:

• Slide Capacity: 30 slides (3 trays × 10 slides each) for multiplex staining and parallel processing
• Reagent Handling: Accommodates 36 reagent containers in sizes 6 mL, 7 mL, or 30 mL, including bulk 5 L containers for extended bioprocessing runs
• Chemical Compatibility: Compatible with all Leica BOND reagents and 70% ethanol cleaning solutions
• Reagent Container Specifications:
• Dead volumes: 555 µL (7 mL), 1618 µL (30 mL), 300 µL (6 mL)
• Reserve volumes: 280 µL for all container sizes
• Waste Management: Integrated system handling 5 L hazardous waste and two 5 L standard bulk waste containers, promoting safe lab operation
• Dimensions: 790 × 1378 × 806 mm (WxHxD), weight 238 kg, optimal for benchtop deployment
• Slide Tracking: Barcode-enabled for precise reagent dispensing and traceability, important for standardized slide preparation and reproducible results in translational research and biopharmaceutical production pipelines
• Temperature Control: Independent slide heating control enhances staining quality

The system is widely adopted in synthetic biology, molecular cloning workflows, and clinical diagnostics laboratories due to its ability to provide consistent, reproducible slide staining results and capability for multiplex tissue analysis. The Leica BOND-III supports advanced biotechnology research needs by automating time-consuming manual staining procedures while maintaining high accuracy and throughput.

Applications:

• Automated IHC for biomarker and protein expression detection
• ISH for gene expression and genetic marker localization
• High-throughput tissue staining for pathology and cancer research
• Multiplex staining protocols in neuroscience, cell imaging, and molecular biology
• Preparation of slides essential in molecular diagnostics, gene editing studies, and biomanufacturing quality control

Despite being sold as-is without warranty due to unavailable software and untested status, this model remains a vital instrument in labs focused on high-throughput tissue analysis and biotechnology-driven research. Contact sales for testing and software support for integration into existing workflows.

This unit integrates seamlessly into bioprocessing and molecular diagnostics labs looking to standardize IHC and ISH protocols and enhance productivity in biopharmaceutical production pipelines. Its robust build and reagent handling capabilities position it as a reliable platform for cutting-edge synthetic biology research and clinical translational studies.

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This automated slide stainer specifically targets scientists, researchers, and laboratory buyers in clinical diagnostics, translational medicine, and biotechnology sectors seeking dependable and scalable staining solutions validated in high-demand research environments.