Lumicks z-Movi Cell Analyzer – Acoustic Force-Based Single-Cell Interaction Measurement System

The Lumicks z-Movi Cell Analyzer is a precision acoustic force-based cell interaction measurement system designed for label-free, real-time quantification of cell–cell binding strength at the single-cell level. This compact instrument is essential for biotechnology and biomedical research fields such as immunology, oncology, cell therapy, and molecular diagnostics. Its ability to deliver quantitative, reproducible, and high-throughput biophysical data makes it a valuable tool widely used in synthetic biology research and biopharmaceutical production pipelines focused on immune cell functionality assessment and therapeutic screening.

Key Technical Features:

• Force Application: Acoustic force precisely controls cell–cell contact and detachment
• Fluorescence Detection: Single-color fluorescence at 635 nm wavelength for cell avidity measurement
• Consumables: Reusable microfluidic chips supporting 50 or 125 runs to optimize throughput
• Throughput: Approximately 20 measurements per day with four chips running five experiments each
• Capacity: Measures interactions involving up to 400 individual cells per experiment
• Dimensions: Compact footprint of 21 x 21 x 32 cm enabling seamless lab integration
• Software: Integrated with Oceon control and analysis software for streamlined data acquisition and processing

Applications and Research Utility:

• Evaluation of T cell–tumor cell interaction strength to advance immunotherapy development
• Characterization of heterogeneous cellular adhesion profiles in molecular cloning workflows
• Screening and functional analysis of immune cells critical in cellular immunotherapy and bioprocessing
• Real-time analysis platform supporting live-cell imaging and biophysical assays in biomanufacturing contexts

This instrument supports researchers in gaining deeper insights into cell–cell interaction heterogeneity and enables robust screening protocols pivotal in synthetic biology and molecular diagnostics. As such, the Lumicks z-Movi is a cornerstone device for laboratories targeting innovation in biopharmaceutical production pipelines, providing reproducibility and ease of operation.

Additional Details:

• The system undergoes rigorous factory-standard testing including camera and optics inspection, software communication verification, and optical coatings integrity checks to ensure reliable operation.
• Offered with warranty, remote instrument setup, and training sessions to facilitate rapid deployment and user proficiency.
• The package includes the z-Movi Analyzer, PC with Oceon software, keyboard, mouse, monitor, and power cord.

This analyzer is highly regarded among molecular biology researchers and biotechnology professionals for its contribution to cell avidity quantification and immune cell functional screening, making it a critical instrument for advanced biomedical engineering and clinical diagnostics laboratories.