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Thermo Scientific EASY Spray Source Model ES081 for Nanoflow HPLC Nano-Electrospray LC-MS

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Thermo Fisher Scientific
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Used
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Product description

Temperature-controlled EASY Spray Source ES081 improves nanoflow HPLC and nano-electrospray ionization for enhanced LC-MS sensitivity.

The Thermo Scientific EASY Spray Source Model ES081 is a precision-engineered nano-electrospray ionization source designed to optimize nanoflow high-performance liquid chromatography (HPLC) separations coupled to mass spectrometry (LC-MS) systems. This source integrates temperature-controlled column-emitter units that enhance separation efficiency and reproducibility, critical for molecular diagnostics and biotechnology applications such as bioprocessing and synthetic biology.

Key technical features include:

  • Integrated temperature-controlled column-emitter units to maintain stable spray conditions and improve chromatographic peak capacity
  • Tool-free, single-connection design enabling rapid and reproducible column replacement, ideal for high-throughput workflows
  • Compatibility with smaller particle sizes and longer columns for increased resolution in complex biological sample analysis
  • Nanoflow HPLC separation coupled with nano-electrospray ionization ensuring outstanding mass spectrometry sensitivity and minimal sample consumption
  • Zero-dead-volume fittings promoting optimal chromatographic performance during extended use
  • Stability and reproducibility vital for biopharmaceutical production pipelines and gene editing research requiring consistent analytical outcomes

This source is widely adopted in biomedical engineering, clinical diagnostics, and cell imaging research where precise and sensitive LC-MS analysis is essential. Its robustness and ease of use support multisite collaborations and complex experimental designs, making it a core component in advanced analytical workflows focusing on molecular cloning and synthetic biology research domains.

With a weight of 18.0 kg (39.68 lbs) and compact shipping dimensions (24.0 x 18.01 x 20.4 cm), the EASY Spray Source ES081 fits efficiently within standard laboratory LC-MS setups and complies with sophisticated analytical instrumentation standards classified under Harmonized Code 902780.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 7 November 2026