Thermo Scientific Exactive Plus EMR Orbitrap High-Resolution Benchtop Mass Spectrometer

The Thermo Scientific Exactive Plus EMR Orbitrap Mass Spectrometer is a high-performance benchtop mass spectrometer designed for advanced biomolecular analysis, including protein characterization, monoclonal antibody studies, and native mass spectrometry. It integrates a high-resolution Orbitrap mass analyzer with a C-Trap for precise ion storage, offering a broad mass range from m/z 350 to 20,000 to support complex biomolecule and biopharmaceutical research workflows.

Key technical features include:

• Orbitrap mass analyzer with C-Trap enabling up to 140,000 FWHM resolution and sub-ppm mass accuracy, critical for molecular diagnostics and bioprocessing applications.
• Extended mass range (m/z 350–20,000) optimized for large biomolecules, making it essential for native protein analysis and biopharmaceutical production pipelines.
• Fast scan speed up to 12 Hz, allowing rapid data acquisition for complex mixture screening and high-throughput metabolite identification.
• Dual polarity operation with positive/negative switching enhances versatility across diverse synthetic biology and cell imaging experiments.
• Thermo Scientific Ion Max API source coupled with H-ESI II dual desolvation probe and S-Lens RF ion guide improve ion transmission efficiency and sensitivity during fluorescence analysis and biotechnology research.
• Advanced vacuum system with 7-region differential vacuum and dual turbo plus rotary vane pumps maintains ultra-high vacuum conditions (<1 × 10⁻⁹ mbar), ensuring instrument stability and longevity in demanding biomedical engineering environments.
• 16-bit digitization signal processing provides precise data fidelity critical for molecular cloning workflows and gene editing studies.

Designed for rugged benchtop use, this Orbitrap mass spectrometer is widely adopted in biotechnology and clinical diagnostics laboratories for routine, high-resolution mass spectrometric analysis. Its capabilities enable researchers to conduct in-depth characterization of proteins, monoclonal antibodies, and metabolites, essential to biopharmaceutical development and synthetic biology research. The instrument supports native MS experiments, making it a valuable tool for elucidating biomolecular structures and interactions.

This pre-owned unit is sold as-is without warranty and has not been fully tested by the vendor. It includes the mass spectrometer and a standard power cord. Proper consumables such as LC-MS grade solvents, calibration standards, and H-ESI spray needles are required for operation.

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